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Active Recombinant Mouse Usp18 Protein, His-tagged

Cat.No. : Usp18-32M
Product Overview : Recombinant mouse Usp18 protein (Ser47 - Ser368) contains an N-terminal 6-His tag was expressed in Spodoptera frugiperda, Sf 21 (baculovirus).
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Description : Involved in the regulation of inflammatory response to interferon type 1. Can efficiently cleave only ISG15 fusions including native ISG15 conjugates linked via isopeptide bonds. Necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms.
Source : Insect cell
Species : Human
Tag : His
Bio-activity : Reaction conditions will need to be optimized for each specific application. We recommend an initial recombinant murine USP18 concentration of 100-250 nM when using ISG15-AMC as a substrate.
Molecular Mass : 38 kDa
Purity : >98%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain.
Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
24 months from date of receipt, -70 centigrade as supplied.
3 months, -70 centigrade under sterile conditions after opening.
Storage Buffer : X mg/mL (X μM) in 50 mM HEPES pH 7.5, 200 mM NaCl, 10% (v/v) Glycerol, 5 mM DTT and 1 mM EDTA
Protein length : Ser47-Ser368
Gene Name : Usp18 ubiquitin specific peptidase 18 [ Mus musculus (house mouse) ]
Official Symbol : Usp18
Synonyms : 43 kDa ISG15-specific protease; ISG15-specific-processing protease; ubiquitin specific protease 15; ubiquitin specific protease 18; ubl thioesterase 18; ubl thiolesterase 18; EC 3.1.2.-; Usp18; ubiquitin specific peptidase 18; UBP43; Ubp15; AW047653; 1110058H21Rik
Gene ID : 24110
mRNA Refseq : NM_011909
Protein Refseq : NP_036039
UniProt ID : Q9WTV6

Not For Human Consumption!

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