Active Recombinant Rat Angptl4, His-tagged

• Cat.No.: Angptl4-104R
• Product Overview: Signal peptide and rat ANGPTL4 (aa 1-405) are fused at the C-terminus to a His-tag.

Specification

• Species: Rat
• Source: E.coli
• Tag: His
• Protein Length: 1-405 a.a.
• Description: ANGPTL4 (Angiopoietin-like protein 4) mainly expressed in endothelial cells (hypoxia-induced). Regulates angiogenesis and modulates tumorigenesis and directly regulates lipid, glucose, and energy metabolism. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage.
• Form: Liquid. 0.2μm-filtered solution in PBS.
• Bio-activity: Activates ERK phosphorylation in THP-1 cells.
• Molecular Mass: ~75kDa (SDS-PAGE)
• Purity: ≥90% (SDS-PAGE)
• Stability: Working aliquots are stable for up to 3 months when stored at -20°C.
• Storage: Short Term Storage: +4°C; Long Term Storage: -20°C. After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

Gene Information

• Gene Name: Angptl4 angiopoietin-like 4 [ Rattus norvegicus ]
• Official Symbol: Angptl4
• Synonyms: ANGPTL4; angiopoietin-like 4; angiopoietin-related protein 4; HFARP; angiopoietin-like protein 4; hepatic fibrinogen/angiopoietin-related protein
• Gene ID: 362850
• mRNA Refseq: NM_199115
• Protein Refseq: NP_954546
• Pathway: PPAR signaling pathway, organism-specific biosystem; PPAR signaling pathway, conserved biosystem
• Function: enzyme inhibitor activity; enzyme inhibitor activity; receptor binding