Active Recombinant Rat Fibroblast Growth Factor 7
| Cat.No. : | Fgf7-372R |
| Product Overview : | Recombinant Rat Fibroblast Growth Factor 7 was expressed inE.Coli.MW=17 kDa. |
- Specification
- Gene Information
- Related Products
- Download
| Species : | Rat |
| Source : | E.coli |
| Tag : | Non |
| Description : | Keratinocyte growth factor is a protein that in humans is encoded by the FGF7 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. |
| Purity : | Purity > 90%. Purified by heparin affinity chromatography. |
| Activity : | The activity of rat FGF-7 at 1-10 ng/ml is determined by tritiated thymidine incorporation using cultured mouse keratinocytes. Maximum stimulation observed at 1 ng/ml. The optimal concentration of this product for use with other cell types must be determined by the end user. |
| Specifity : | 45102 binds to keratinocytes and most parenchymal epithelial cells; binds specific splice variant of FGF receptor expessed in epithelial cells (FGFr2IIIb). |
| Content : | Protein quantitation was carried out by two independent methods: 1. UV spectroscopy at 280 nm. 2. Analysis by RP-HPLC, using a calibrated solution of IGF-II as a Reference Standard. |
| Storage : | This product is stable for at least one year at -20℃ to -70℃. Keep frozen until use. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles. |
| Gene Name | Fgf7 fibroblast growth factor 7 [ Rattus norvegicus ] |
| Synonyms | Fgf7; fibroblast growth factor 7; Kgf; fibroblast growth factor 7; FGF-7; HBGF-7; keratinocyte growth factor; heparin-binding growth factor 7 |
| Gene ID | 29348 |
| mRNA Refseq | NM_022182 |
| Protein Refseq | NP_071518 |
| UniProt ID | Q02195 |
| Chromosome Location | 3q36 |
| Pathway | MAPK signaling pathway; Melanoma; Pathways in cancer; Regulation of actin cytoskeleton |
| Function | chemoattractant activity; growth factor activity; heparin binding; protein binding; type 2 fibroblast growth factor receptor binding |
Not For Human Consumption!
Inquiry
- Reviews (0)
- Q&As (0)
Ask a Question for All Fgf7 Products
Required fields are marked with *
My Review for All Fgf7 Products
Required fields are marked with *
Recently Viewed
