Active Recombinant Rat Il4r protein, hFc-tagged
|Product Overview :||Recombinant Rat Il4r protein(Q63257-1)(Met1-Arg232), fused with hFc tag, was expressed in HEK293.|
- Gene Information
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|Form :||Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.|
|Bio-activity :||Measured by its binding ability in a functional ELISA.Immobilized mouse IL4-His at 10 μg/mL (100 μl/well) can bind rat IL4R-Fc, The EC50 of rat IL4R-Fc is 0.12-0.29 μg/mL.|
|Molecular Mass :||The recombinant rat IL4R/Fc is a disulfide-linked homodimer. The reduced monomer comprises 448 amino acids and has a predicted molecular mass of 50.9 kDa. The apparent molecular mass of the protein is approximately 66 kDa in SDS-PAGE under reducing conditions.|
|Protein Length :||Met1-Arg232|
|Endotoxin :||< 1.0 EU per μg of the protein as determined by the LAL method|
|Purity :||> 90 % as determined by SDS-PAGE|
|Storage :||Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|Reconstitution :||It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.|
|Gene Name :||Il4r interleukin 4 receptor [ Rattus norvegicus (Norway rat) ]|
|Official Symbol :||Il4r|
|Synonyms :||Il4r; Il4ra; interleukin 4 receptor; interleukin-4 receptor subunit alpha; IL-4RA; IL-4R-alpha; IL-4R subunit alpha; IL-4 receptor subunit alpha; interleukin 4 receptor, alpha; interleukin-4 receptor alpha chain|
|Gene ID :||25084|
|mRNA Refseq :||NM_133380|
|Protein Refseq :||NP_596871|
|UniProt ID :||Q63257|
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (6)Ask a question
IL4R is a synthetic protein that mimics the IL-4 signaling pathway in nature and binds to the IL-4 receptor in cells, which can be used to study the IL-4 signaling pathway and related diseases.
Common IL4R production technologies include prokaryotic expression systems and mammalian cell expression systems.
This protein is used in tumor immunotherapy, which can promote anti-tumor immune response and enhance the anti-tumor effect of cytotoxic T lymphocytes.
It is mainly used in immunology, drug research and other fields. It is also widely used in vaccines, biotechnology, cancer treatment and so on.
IL4R is used to treat severe pheochromocytome-induced aerodoritis and was approved by the FDA as the first drug to treat this disease.
IL4R cannot generally be administered orally, and needs to be administered by injection or intravenous drip.
Customer Reviews (3)Write a review
Easy to attach to the surface of cells or materials. -
It has growth factor activity to promote cell growth and proliferation. -
In animals or humans caused by the prone production of antibodies. -
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