BRD4 bromodomains 1 and 2 TR-FRET Assay Kit Kit-1932

BRD4 bromodomains 1 and 2 TR-FRET Assay Kit

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Cat.No. : Kit-1932 Optional Service: Optional requirements on this protein
Size : 9600 wells
Description : The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. The isolated individual or tandem bromodomains of BRD2 and BRD4 have been shown to bind acetylated histone tails, serving to couple histone acetylation marks to the transcriptional regulation of target promoters. Small molecule inhibitors of bromodomain/histone interactions hold promise as useful therapeutics for human disease. The BRD4 bromodomains 1 and 2 TR-FRET Assay Kit is a homogeneous, TR-FRET assay method amenable to rapid characterization of inhibitors of bromodomain/acetylated peptide interaction in a high throughput format. This screening assay is robust, displaying a Z >0.6.
Storage : -80°C
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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