CD105 protein-coupled magnetic MicroBeads

Species :	Human
Capacity :	for 1×10^9 total cells
Background :	The CD105 antigen (endoglin) serves as a receptor for the growth and differentiation factors TGF-β1 and TGF-β3, and is expressed on mature endothelial cells, on MSCs with mesodermal differentiation capacity, and on some leukemic cells of B lymphoid and myeloid origin. The CD105 MicroBeads recognize the same molecular antigen as anti-SH2 antibodies-the most commonly employed antigen for the definition of cultivated MSCs.
Application :	CD105 MicroBeads can be used for studies on mesengenesis and for in vitro investigations on hematological disorders. CD105+ bone marrow cells also show multipotent differentiation in vitro and the capacity to form bone in vivo without prior cultivation or differentiation.