"TMOD1" Related Products


Recombinant Human Tropomodulin 1, T7-tagged

Cat. No.: TMOD1-3002H
Product Overview: Recombinant Human TMOD1 protein was expressed in E.coli with T7-tag at the N-terminus. The molecular weight is 40569 Da(359 aa).
Description: Tropomodulin-1 is a protein that in humans is encoded by the TMOD1 gene. Human erythrocyte tropomodulin is a 43-kD tropomyosin-regulating protein. It may modulate the association of tropomyosin with the spectrin-actin complex in the erythrocyte membrane skeleton, and thus the viscoelastic properties of erythrocytes. Tropomodulin is associated with the pointed end of the actin filaments. It binds specifically to the N terminus of tropomyosin and blocks the elongation and depolarization of tropomyosin-coated actin filaments.
Sequences of amino acids: 1-359 aa
Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3. 10mM DTT.
Purity: 90%
Gene Name: TMOD1 tropomodulin 1 [ Homo sapiens ]
Synonyms: TMOD; ETMOD; D9S57E; E-Tmod; e-tropomodulin; OTTHUMP00000021743; OTTHUMP00000021744; erythrocyte tropomodulin; tropomodulin-1
Gene ID: 7111
mRNA Refseq: NM_003275
Protein Refseq: NP_003266
MIM: 190930
UniProt ID: P28289
Chromosome Location: 9q22.3
Pathway: Reactome Event:Muscle contraction
Function: actin binding; tropomyosin binding

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