"TSN" Related Products


Recombinant Human Translin, T7-tagged

Cat. No. : TSN-3001H
Product Overview : Recombinant Human TSN protein was expressed in E.coli with T7-tag at the N-terminus. The molecular weight is 26183 Da(228 aa).
Description : Translin is a protein that in humans is encoded by the TSN gene. This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms.
Sequences of amino acids : 1-228 aa
Formulation : 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3.
Purity : 95%
Gene Name : TSN translin [ Homo sapiens ]
Synonyms : RCHF1; TBRBP; TRSLN; BCLF-1; REHF-1; translin; OTTHUMP00000203715; OTTHUMP00000203716; recombination hotspot-binding protein; recombination hotspot associated factor
Gene ID : 7247
mRNA Refseq : NM_004622
Protein Refseq : NP_004613
MIM : 600575
UniProt ID : Q15631
Chromosome Location : 2q21.1
Function : DNA binding; mRNA binding; protein binding; sequence-specific DNA binding

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