| Cat. No.: | PFDN4-3404H |
| Product Overview: | Recombinant human PFDN4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Description: | Prefoldin subunit 4, also known PFDN4, is a member of the prefoldin beta subunit family. PFDN4 is a heterohexameric chaperone protein which has the ability to capture unfolded actin and is a possible transcription factor. Six prefoldin polypeptides, prefoldin 1-6, have been identified. |
| Source: | E.coli. |
| Form: | Liquid. In 20mM Tris-HCl buffer (pH 7.5) containing 1mM DTT, 10% glycerol, 50mM NaCl. |
| Molecular Weight: | 17.4 kDa (154aa) confirmed by MALDI-TOF. |
| Purity: | > 90% by SDS - PAGE. |
| Concentration: | 1 mg/ml (determined by Bradford assay). |
| Sequences Of Amino Acids: | MGSSHHHHHH SSGLVPRGSH MAATMKKAAA EDVNVTFEDQ QKINKFARNT SRI TELKEEI EVKKKQLQNL EDACDDIMLA DDDCLMIPYQIGDVFISHSQ EETQ EML EEA KKNLQEEIDA LESRVESIQR VLADLKVQLY AKFGSNINLE ADES. |
| Storage: | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
| Pathways: | Metabolism of proteins |
| Gene Name: | PFDN4 prefoldin subunit 4 [ Homo sapiens ] |
| Synonyms: | prefoldin subunit 4; C1; PFD4; PFDN4;prefoldin subunit 4; prefoldin 4; protein C-1; Protein C-1; C-1 |
| Gene ID: | 5203 |
| mRNA Refseq: | NM_002623 |
| Protein Refseq: | NP_002614 |
| MIM: | 604898 |
| UniProt ID: | Q9NQP4 |
| Chromosome Location: | 20q13.2 |
| Function: | chaperone binding; unfolded protein binding |
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