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Recombinant Human ADP-ribosylation Factor 1, His-tagged
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Cat. No. : | ARF1-2769H |
Product Overview : | Recombinant human ARF1 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 22.8 kDa (201aa). |
Description : | ARF1, also known as ADP-ribosylation factor 1, is a small guanine nucleotide-binding protein that enhances the enzymatic activities of cholera toxin. It is essential and ubiquitous in eukaryotes, as this protein is involved in vesicular transport and functioning via phospholipase D activation. ARF1 plays a role in membrane traffic and organelle integrity and are intimately tied to their reversible association with membranes and distinct interactions with membrane phospholipids. |
Source : | E.coli. |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl,1mM DTT. |
Purity : | > 90% by SDS - PAGE. |
Concentration : | 1.0 mg/ml (determined by Bradford assay). |
Sequences Of Amino Acids : | MGSSHHHHHH SSGLVPRGSH MGNIFANLFK GLFGKKEMRI LMVGLDAAGK TTIL YK LKLG EIVTTIPTIG FNVETVEYKN ISFTVWDVGGQDKIRPLWRH YFQNTQGLIF VV DSNDRERV NEAREELMRM LAEDELRDAV LLVFANKQDL PNAMNAAEIT DKL GLHSLRH RNWYIQATCA TSGDGLYEGL DWLSNQLRNQ K. |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Pathways : | Vibrio cholerae infection; HIV Infection; Membrane Trafficking |
PDB rendering based on 1hur. : |
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Gene Name : | ARF1 ADP-ribosylation factor 1 [ Homo sapiens ] |
Synonyms : | ADP-ribosylation factor 1; ARF1 |
Gene ID : | 375 |
mRNA Refseq : | NM_001024226 |
Protein Refseq : | NP_001019397 |
MIM : | 103180 |
UniProt ID : | P84077 |
Chromosome Location : | 1q42 |
Function : | GTP binding; GTPase activity; nucleotide binding; protein binding; receptor signaling protein activity |
◆ Recombinant Protein
Arf1-634M | Recombinant Mouse Arf1 Protein, MYC/DDK-tagged | +Inquiry |
ARF1-378R | Recombinant Rhesus monkey ARF1 Protein, His-tagged | +Inquiry |
ARF1-9799H | Recombinant Human ARF1, GST-tagged | +Inquiry |
ARF1-1837M | Recombinant Mouse ARF1 Protein | +Inquiry |
ARF1-11499Z | Recombinant Zebrafish ARF1 | +Inquiry |
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◆ Lysates
ARF1-8761HCL | Recombinant Human ARF1 293 Cell Lysate | +Inquiry |
ARF1-8760HCL | Recombinant Human ARF1 293 Cell Lysate | +Inquiry |
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