Recombinant Human ADP-ribosylation Factor 1, His-tagged ARF1-2769H

Recombinant Human ADP-ribosylation Factor 1, His-tagged

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Recombinant Human ADP-ribosylation Factor 1, His-tagged

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Cat. No. : ARF1-2769H
Product Overview : Recombinant human ARF1 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 22.8 kDa (201aa).
Description : ARF1, also known as ADP-ribosylation factor 1, is a small guanine nucleotide-binding protein that enhances the enzymatic activities of cholera toxin. It is essential and ubiquitous in eukaryotes, as this protein is involved in vesicular transport and functioning via phospholipase D activation. ARF1 plays a role in membrane traffic and organelle integrity and are intimately tied to their reversible association with membranes and distinct interactions with membrane phospholipids.
Source : E.coli.
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl,1mM DTT.
Purity : > 90% by SDS - PAGE.
Concentration : 1.0 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MGNIFANLFK GLFGKKEMRI LMVGLDAAGK TTIL YK LKLG EIVTTIPTIG FNVETVEYKN ISFTVWDVGGQDKIRPLWRH YFQNTQGLIF VV DSNDRERV NEAREELMRM LAEDELRDAV LLVFANKQDL PNAMNAAEIT DKL GLHSLRH RNWYIQATCA TSGDGLYEGL DWLSNQLRNQ K.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways : Vibrio cholerae infection; HIV Infection; Membrane Trafficking
PDB rendering based on 1hur. :

Gene Name : ARF1 ADP-ribosylation factor 1 [ Homo sapiens ]
Synonyms : ADP-ribosylation factor 1; ARF1
Gene ID : 375
mRNA Refseq : NM_001024226
Protein Refseq : NP_001019397
MIM : 103180
UniProt ID : P84077
Chromosome Location : 1q42
Function : GTP binding; GTPase activity; nucleotide binding; protein binding; receptor signaling protein activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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