| Cat. No. : |
ARF1-2769H |
| Product Overview : |
Recombinant human ARF1 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 22.8 kDa (201aa). |
| Description : |
ARF1, also known as ADP-ribosylation factor 1, is a small guanine nucleotide-binding protein that enhances the enzymatic activities of cholera toxin. It is essential and ubiquitous in eukaryotes, as this protein is involved in vesicular transport and functioning via phospholipase D activation. ARF1 plays a role in membrane traffic and organelle integrity and are intimately tied to their reversible association with membranes and distinct interactions with membrane phospholipids. |
| Source : |
E.coli. |
| Form : |
Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl,1mM DTT. |
| Purity : |
> 90% by SDS - PAGE. |
| Concentration : |
1.0 mg/ml (determined by Bradford assay). |
| Sequences Of Amino Acids : |
MGSSHHHHHH SSGLVPRGSH MGNIFANLFK GLFGKKEMRI LMVGLDAAGK TTIL YK LKLG EIVTTIPTIG FNVETVEYKN ISFTVWDVGGQDKIRPLWRH YFQNTQGLIF VV DSNDRERV NEAREELMRM LAEDELRDAV LLVFANKQDL PNAMNAAEIT DKL GLHSLRH RNWYIQATCA TSGDGLYEGL DWLSNQLRNQ K. |
| Storage : |
Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
| Pathways : |
Vibrio cholerae infection; HIV Infection; Membrane Trafficking |
| PDB rendering based on 1hur. : |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.