Recombinant Human ADP-ribosylation Factor 1, His-tagged ARF1-2769H

Cat. No.:	ARF1-2769H
Product Overview:	Recombinant human ARF1 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 22.8 kDa (201aa).
Description:	ARF1, also known as ADP-ribosylation factor 1, is a small guanine nucleotide-binding protein that enhances the enzymatic activities of cholera toxin. It is essential and ubiquitous in eukaryotes, as this protein is involved in vesicular transport and functioning via phospholipase D activation. ARF1 plays a role in membrane traffic and organelle integrity and are intimately tied to their reversible association with membranes and distinct interactions with membrane phospholipids.
Source:	E.coli.
Form:	Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl,1mM DTT.
Purity:	> 90% by SDS - PAGE.
Concentration:	1.0 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids:	MGSSHHHHHH SSGLVPRGSH MGNIFANLFK GLFGKKEMRI LMVGLDAAGK TTIL YK LKLG EIVTTIPTIG FNVETVEYKN ISFTVWDVGGQDKIRPLWRH YFQNTQGLIF VV DSNDRERV NEAREELMRM LAEDELRDAV LLVFANKQDL PNAMNAAEIT DKL GLHSLRH RNWYIQATCA TSGDGLYEGL DWLSNQLRNQ K.
Storage:	Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways:	Vibrio cholerae infection; HIV Infection; Membrane Trafficking

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Gene Name:	ARF1 ADP-ribosylation factor 1 [ Homo sapiens ]
Synonyms:	ADP-ribosylation factor 1; ARF1
Gene ID:	375
mRNA Refseq:	NM_001024226
Protein Refseq:	NP_001019397
MIM:	103180
UniProt ID:	P84077
Chromosome Location:	1q42
Function:	GTP binding; GTPase activity; nucleotide binding; protein binding; receptor signaling protein activity