Recombinant Human BDH2 protein, His-tagged BDH2-3452H

Recombinant Human BDH2 protein, His-tagged

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Recombinant Human BDH2 protein, His-tagged

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Cat.No. : BDH2-3452H
Product Overview : Recombinant Human BDH2(1-245aa) fused with His tag at N-terminal was expressed in E. coli.
Description : BDH2, also known as DHRS6, belongs to the short-chain dehydrogenases/reductases (SDR) family. This protein may play an important role in the peripheral utilization of 3-hydroxybutyrate. The cytoplasmic localization with its high ratio of oxidized NAD+, the NAD+ dependence and the kinetic parameters of BDH2 make it suitable to convert high levels of circulating 3-hydroxybutyrate into acetoacetate.
Source : E. coli
Species : Human
Tag : His
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl
Molecular Mass : 28.8 kDa (265aa), confirmed by MALDI-TOF
AA Sequence : MGSSHHHHHH SSGLVPRGSHEVERLDVLFN VAGFVHHGTV LDCEEKDWDF SMNLNVRSMY LMIKAFLPKM LAQKSGNIIN MSSVASSVKG VVNRCVYSTT KAAVIGLTKS MGRLDGKVII LTAAAQGIGQ AAALAFAREG AKVIATDINE SKLQELEKYP GIQTRVLDVT KKKQIDQFANVAADFIQQGI RCNCVCPGTV DTPSLQERIQ ARGNPEEARN DFLKRQKTGR FATAEEIAML CVYLASDESA YVTGNPVIID GGWSL
Purity : >95% by SDS - PAGE
Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 1.0 mg/ml (determined by BCA assay)
Gene Name : BDH2 3-hydroxybutyrate dehydrogenase, type 2 [ Homo sapiens ]
Official Symbol : BDH2
Synonyms : BDH2; 3-hydroxybutyrate dehydrogenase, type 2; dehydrogenase/reductase (SDR family) member 6 , DHRS6; 3-hydroxybutyrate dehydrogenase type 2; FLJ13261; PRO20933; SDR15C1; short chain dehydrogenase/reductase family 15C; member 1; UCPA OR; UNQ6308; oxidoreductase UCPA; R-beta-hydroxybutyrate dehydrogenase; dehydrogenase/reductase SDR family member 6; dehydrogenase/reductase (SDR family) member 6; short chain dehydrogenase/reductase family 15C, member 1; DHRS6; EFA6R; UCPA-OR;
Gene ID : 56898
mRNA Refseq : NM_020139
Protein Refseq : NP_064524
MIM :
UniProt ID : Q9BUT1
Chromosome Location : 4q24
Pathway : Butanoate metabolism, organism-specific biosystem; Butanoate metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Synthesis and degradation of ketone bodies, organism-specific biosystem; Synthesis and degradation of ketone bodies, conserved biosystem; ketolysis, organism-specific biosystem; ketolysis, conserved biosystem;
Function : 3-hydroxybutyrate dehydrogenase activity; NAD binding; oxidoreductase activity; oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;

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