"EIF4E" Related Products

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Recombinant Human EIF4E, His-tagged

Cat. No.: EIF4E-2775H
Product Overview: Recombinant human EIF4E protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography. MW = 27.2 kDa(237aa).
Description: EIF4E, a member of eukaryotic initiation factor 4 families, modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. This protein recognizes and binds to the 7 methyl GTP cap structure of eukaryotic mRNAs, thereby mediating the initiation of translation. It facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
Source: E.coli.
Form: Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 10% Glycerol.
Purity: > 85% by SDS - PAGE.
Concentration: 0.5 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MATVEPETTP TPNPPTTEEE KTESNQEVAN PEH YIKHPLQ NRWALWFFKN DKSKTWQANL RLISKFDTVEDFWALYNHIQ LSSN LM PG CD YSLFKDGIEP MWEDEKNKRG GRWLITLNKQ QRRSDLDRFW LET LL CLIGE SFDDYSDDVC GAVVNVRAKG DKIAIWTTEC ENREAVTHIG RVYKERLGLP PKIVIGYQSH ADTATKSGST TKNRFVV.
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: EIF4E eukaryotic translation initiation factor 4E [ Homo sapiens ]
Synonyms: eukaryotic translation initiation factor 4E; CBP; EIF4F; EIF4E1; EIF4EL1; MGC111573; EIF4E; eIF-4E; eIF-4F 25 kDa subunit; mRNA cap-binding protein; eukaryotic translation initiation factor 4E-like 1; eIF4E
Gene ID: 1977
mRNA Refseq: NM_001130678
Protein Refseq: NP_001124150
MIM: 133440
UniProt ID: P06730
Chromosome Location: 4q21-q25
Pathway: Insulin signaling pathway; mTOR signaling pathway; Gene Expression; Metabolism of RNA; Metabolism of proteins; Signaling by Insulin receptor
Function: translation initiation factor activity; protein binding; RNA cap binding

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