Mouse Anti-Human MRP1 Monoclonal Antibody


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Mouse Anti-Human MRP1 Monoclonal Antibody

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Cat. No. : CAB-905MH
Specificity : Human multidrug resistanec-associated protein 1
Host : Mouse
Clonality : Monoclonal
Positive Control : Breast tumors
Staining Pattern : Cytoplasmic, Cell membrane
Specificity Note : The MRP molecule, an integral membrane glycophosphoprotein belonging to the same superfamily of ATP-binding cassette transmembrane transporter proteins as P-glycoprotein, is overexpressed in many P-glycoprotein-negative, multidrug resistant cell lines and tumours. It is believed that the main function of MRP in drug resistance is that of a plasma membrane drug efflux pump.
Applications : Formalin-fixed paraffin-embedded tissue, or IHC frozen sections. No antigen retrieval necessary.
Recommended Usage : IHC test, research use only. Incubate with samples at RT for 60min or at 4℃ overnight.
Storage : 2-8℃ for 12 months.
Gene Name : MRP1 Multidrug resistance-associated protein-1 [ Homo sapiens ]
Synonyms : MRP1; ATP-binding cassette, sub-family C (CFTR/MRP), member 1; MRP; multidrug resistance associated protein 1; GS-X; Leukotriene C(4) transporter; ATP-binding cassette sub-family C member 1; multidrug resistance-associated protein 1; multiple drug resistance-associated protein; ABC29; ABCC; DKFZp781G125; multiple drug resistance protein 1; DKFZp686N04233; multidrug resistance protein
Gene ID : 4363
mRNA Refseq : NM_004996.3
Protein Refseq : NP_004987.2
MIM : 158343
UniProt ID : P33527
Chromosome Location : 16p13.1
Function : ATP binding;ATPase activity;ATPase activity, coupled to transmembrane movement of substances;hydrolase activity;nucleotide binding;transporter activity

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