Recombinant Human 6-phosphogluconolactonase, His-tagged

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Recombinant Human 6-phosphogluconolactonase, His-tagged

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Cat. No. : PGLS-2843H
Product Overview : Recombinant human PGLS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW = 29.7 kDa (278aa) confirmed by MALDI-TOF.
Description : 6-phosphogluconolactonase, also known PGLS, is an enzyme in the second step pentose phosphate pathway, which is essential for the synthesis of nucleotide sugars and NADPH, the main source of reducing power. It converts 6-phosphogluconolactone to 6-phosphogluconate.
Source : E.coli.
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MAAPAPGLIS VFSSSQELGA ALAQLVAQRA ACCLAGARAR FALGLSGGSL VSMLARELPA AVAPAGPASL ARWTLGFCDE RLVPFDHAES TYGLYRTHLL SRLPIPESQV ITINPELPVE EAAEDYAKKL RQAFQGDSIP VFDLLILGVG PDGHTCSLFP DHPLLQEREK IVAPISDSPK PPPQRVTLTL PVLNAARTVI FVATGEGKAA VLKRILEDQE ENPLPAALVQ PHTGKLCWFL DEAAARLLTV PFEKHSTL
Purity : > 95% by SDS – PAGE.
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 100mM NaCl.
Concentration : 1 mg/ml (determined by Bradford assay).
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : PGLS 6-phosphogluconolactonase [ Homo sapiens ]
Synonyms : PGLS; 6-phosphogluconolactonase; 6PGL; EC 3.1.1.31
Gene ID : 25796
mRNA Refseq : NM_012088
Protein Refseq : NP_036220
MIM : 604951
UniProt ID : O95336
Chromosome Location : 19p13.2
Pathway : Metabolic pathways; Pentose phosphate pathway
Function : 6-phosphogluconolactonase activity; hydrolase activity; monosaccharide binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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