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Recombinant Human PTP4A1(2-173), His-tagged

Cat.No. : PTP4A1-504H
Product Overview : Recombinant human PTP4A1 protein(2-173) with N-terminal His tag was expressed in anE.coliexpression system, MW= 19.8 kDa.
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  • Gene Information
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Cat. No. : PTP4A1-504H
Description : Protein tyrosine phosphatase type IVA 1 is an enzyme that in humans is encoded by the PTP4A1 gene. The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation.
Source : E.coli.
Purity : > 90%.
Formulation : 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 20% glycerol, and 3 mM DTT.
Specific Activity : 0.168 pmol/min/μg, Assay conditions: enzyme was incubated in50mM Tris pH7.4, 150mM NaCl 5mM DTT, and 12.5mM PNPP as a substrate for 2h at 37°C. Absorbance was read by Tecan spectraphotometer at 405 nm wavelength.
Application : Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Storage : >6 months at –80°C.
Gene Name : PTP4A1 protein tyrosine phosphatase type IVA, member 1 [ Homo sapiens ]
Synonyms : PTP4A1; protein tyrosine phosphatase type IVA, member 1; HH72; PRL1; PRL-1; PTPCAAX1; PTP(CAAX1); DKFZp779M0721; PTP(CAAXI); protein-tyrosine phosphatase 4a1; Protein tyrosine phosphatase IVA1; protein tyrosine phosphatase type IVA protein 1; protein-tyrosine phosphatase of regenerating liver 1; EC 3.1.3.48
Gene ID : 7803
mRNA Refseq : NM_003463
Protein Refseq : NP_003454
MIM : 601585
UniProt ID : Q93096
Chromosome Location : 6q12
Function : hydrolase activity; protein tyrosine phosphatase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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