"PTP4A1" Related Products


Recombinant Human PTP4A1(2-173), His-tagged

Cat. No.: PTP4A1-504H
Product Overview: Recombinant human PTP4A1 protein(2-173) with N-terminal His tag was expressed in anE.coliexpression system, MW= 19.8 kDa.
Description: Protein tyrosine phosphatase type IVA 1 is an enzyme that in humans is encoded by the PTP4A1 gene. The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation.
Source: E.coli.
Purity: > 90%.
Formulation: 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 20% glycerol, and 3 mM DTT.
Specific Activity: 0.168 pmol/min/μg, Assay conditions: enzyme was incubated in50mM Tris pH7.4, 150mM NaCl 5mM DTT, and 12.5mM PNPP as a substrate for 2h at 37°C. Absorbance was read by Tecan spectraphotometer at 405 nm wavelength.
Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Storage: >6 months at –80°C.
Gene Name: PTP4A1 protein tyrosine phosphatase type IVA, member 1 [ Homo sapiens ]
Synonyms: PTP4A1; protein tyrosine phosphatase type IVA, member 1; HH72; PRL1; PRL-1; PTPCAAX1; PTP(CAAX1); DKFZp779M0721; PTP(CAAXI); protein-tyrosine phosphatase 4a1; Protein tyrosine phosphatase IVA1; protein tyrosine phosphatase type IVA protein 1; protein-tyrosine phosphatase of regenerating liver 1; EC
Gene ID: 7803
mRNA Refseq: NM_003463
Protein Refseq: NP_003454
MIM: 601585
UniProt ID: Q93096
Chromosome Location: 6q12
Function: hydrolase activity; protein tyrosine phosphatase activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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