Recombinant Human Smad Nuclear Interacting Protein 1, His-tagged


Home / Products / Recombinant Proteins / Recombinant Human Smad Nuclear Interacting Protein 1, His-tagged

Recombinant Human Smad Nuclear Interacting Protein 1, His-tagged

SNIP1 Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat. No. : SNIP1-5127H
Product Overview : Recombinant human SNIP1 protein,fused to His-tag at N-terminus, was expressed in E. coli and purified byusing conventional chromatography techniques.
Description : SNIP1 is smad nuclear interactingprotein contains a forkhead-associated (FHA) domain and acts as a nuclearinhibitor of CBP/p300. This protein is an inhibitor of the TGF-beta signaltransduction pathway and is important in suppressing transcriptionalactivation dependent on the co-activators CBP and p300. Inhibition ofNF-kappa B activity is a function of the N-terminal domain of SNIP1 andinvolves competition of SNIP1 and the NF-kappa B subunit, RelA/p65, for bindingto p300, similar to the mechanism of inhibition of Smad signaling by SNIP1.
Concentration : 1 mg/ml
Source : Human
Host : E.coli
Form : Suppliedas a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 2mM DTT, 20% glyceroland 100mM NaCl.
Purity : > 90% by SDS -PAGE
Molecular Mass : 18.8 kDa(160aa), confirmed by MALDI-TOF.
Applications : SDS-PAGE
Storage : Storeat 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg Cor - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
OfficialSymbol : SNIP1
Pathways : Regulation ofnuclear SMAD2/3 signaling; TGF-beta Receptor Signaling Pathway
Gene Name : SNIP1 Smad nuclear interactingprotein 1 [ Homo sapiens ]
Synonyms : SNIP1;Smad nuclear interacting protein 1; FLJ12553;dJ423B22.2; RP3-423B22.3; smad nuclear-interacting protein 1; FHAdomain-containing protein SNIP1; Smad nuclear interacting protein (SNIP1); Smad nuclear-interacting protein 1; OTTHUMP00000004404
Gene ID : 79753
mRNA Refseq : NM_024700
Protein Refseq : NP_078976
MIM : 608241
UniProt ID : Q8TAD8
Chromosome Location : 1p34.3
Function : proteinbinding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Online Inquiry

  • Note: There will be extra charge for optional service!

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2021 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy