"PTPN9" Related Products

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Recombinant Human PTPN9, GST-tagged

Cat. No. : PTPN9-1857H
Product Overview : Recombinant human PTPN9 protein(a.a.285-593) with N-terminal GST tag was expressed in anE.coliexpression system, MW=60.3 kDa.
Description : Tyrosine-protein phosphatase non-receptor type 9 is an enzyme that in humans is encoded by the PTPN9 gene. The protein is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
Source : E.coli.
Formulation : 25 mM Tris-HCl, pH 8.0, 75 mM NaCl, 0.05% Tween-20, 50% glycerol, 2 mM EDTA, 1 mM DTT, 10 mM glutathione.
Purity : > 70% by SDS-PAGE.
Specific Activity : 2 U/ug. One unit will hydrolyze 1 nmol p-nitrophenyl phosphate per minute at pH 7.4 and 30°C. Assay buffer: 50 mM HEPES, pH 7.4, 2 mM EDTA, 3 mM DTT, 100 mM NaCl, 50 mM pNPP.
Application : Useful for the study of enzyme kinetics, regulation, to dephosphorylate target substrates and for screening inhibitors.
Storage : >6 months at –80°C.
PDB rendering based on 2pa5 :

Gene Name : PTPN9 protein tyrosine phosphatase, non-receptor type 9 [ Homo sapiens ]
Synonyms : protein tyrosine phosphatase, non-receptor type 9; MEG2; PTPMEG2; PTPN9; tyrosine-protein phosphatase non-receptor type 9; PTPase MEG2; PTPase-MEG2; protein-tyrosine phosphatase MEG2; EC 3.1.3.48
Gene ID : 5780
mRNA Refseq : NM_002833
Protein Refseq : NP_002824
MIM : 600768
UniProt ID : P43378
Chromosome Location : 15q24.2
Function : hydrolase activity; non-membrane spanning protein tyrosine phosphatase activity; protein binding; protein tyrosine phosphatase activity

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