Recombinant Human ADP-Ribosylation Factor-Like 6, His-tagged ARL6-4974H

Recombinant Human ADP-Ribosylation Factor-Like 6, His-tagged

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Recombinant Human ADP-Ribosylation Factor-Like 6, His-tagged

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Cat. No. : ARL6-4974H
Product Overview : Recombinant humanARL6 protein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography.
Description : ARL6, also knownADP-ribosylation factor-like protein 6, belongs to the ARF family ofGTP-binding proteins. This protein is known to play essential roles inmodulating membrane trafficking and cytoskeletal functions. Mutation in ARL6causes Bardet-Biedl syndrome (BBS3). BBS is a pleiotropic genetic disordercharacterized by obesity, photoreceptor degeneration, polydactyly,hypogenitalism, renal abnor-malities and developmental delay.
Concentration : 0.5 mg/ml
Source : Human
Host : E. coli
Form : Supplied as a liquidin 20 mM Tris-HCl buffer, pH 8.0, containing 20% glycerol, 0.2 M NaCl and 5mM DTT.
Purity : > 90% by SDS-PAGE
Sequence : 1-186 amino acids:MGSSHHHHHH SSGLVPRGSH MGLLDRLSVL LGLKKKEVHV LCLGLDNSGK TTIINKLKPS NAQSQNILPTIGFSIEKFKS SSLSFTVFDM SGQGRYRNLW EHYYKEGQAI IFVIDSSDRL RMVVAKEELD TLLNHPDIKHRRIPILFFAN KMDLRDAVTS VKVSQLLCLE NIKDKPWHIC ASDAIKGEGL QEGVDWLQDQ IQTVKT
Molecular Mass : 23.2 kDa (206 aa),confirmed by MALDI-TOF
Applications : SDS-PAGE
Storage : Store at 4 deg C forshort term storage (1/2 weeks). Aliquot and store at -20 deg C or -70 deg Cfor long term storage. Avoid repeated freeze/thaw cycles.
OfficialSymbol : ARL6
PDB rendering basedon 2h57. :

Gene Name : ARL6 ADP-ribosylation factor-like 6 [ Homosapiens ]
Synonyms : ARL6;ADP-ribosylation factor-like 6; BBS3; RP55; MGC32934; Bardet-Biedl syndrome 3protein; OTTHUMP00000214308; OTTHUMP00000214309; OTTHUMP00000214310;ADP-ribosylation factor-like protein 6
Gene ID : 84100
mRNA Refseq : NM_032146
Protein Refseq : NP_115522
MIM : 608845
UniProt ID : Q9H0F7
Chromosome Location : 3q11.2
Function : GTP binding; metalion binding; nucleotide binding; phospholipid binding

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