"ARL6" Related Products

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Recombinant Human ADP-Ribosylation Factor-Like 6, His-tagged

Cat. No.: ARL6-4974H
Product Overview: Recombinant humanARL6 protein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography.
Description: ARL6, also knownADP-ribosylation factor-like protein 6, belongs to the ARF family ofGTP-binding proteins. This protein is known to play essential roles inmodulating membrane trafficking and cytoskeletal functions. Mutation in ARL6causes Bardet-Biedl syndrome (BBS3). BBS is a pleiotropic genetic disordercharacterized by obesity, photoreceptor degeneration, polydactyly,hypogenitalism, renal abnor-malities and developmental delay.
Concentration: 0.5 mg/ml
Source: Human
Host: E. coli
Form: Supplied as a liquidin 20 mM Tris-HCl buffer, pH 8.0, containing 20% glycerol, 0.2 M NaCl and 5mM DTT.
Purity: > 90% by SDS-PAGE
Sequence: 1-186 amino acids:MGSSHHHHHH SSGLVPRGSH MGLLDRLSVL LGLKKKEVHV LCLGLDNSGK TTIINKLKPS NAQSQNILPTIGFSIEKFKS SSLSFTVFDM SGQGRYRNLW EHYYKEGQAI IFVIDSSDRL RMVVAKEELD TLLNHPDIKHRRIPILFFAN KMDLRDAVTS VKVSQLLCLE NIKDKPWHIC ASDAIKGEGL QEGVDWLQDQ IQTVKT
Molecular Mass: 23.2 kDa (206 aa),confirmed by MALDI-TOF
Applications: SDS-PAGE
Storage: Store at 4 deg C forshort term storage (1/2 weeks). Aliquot and store at -20 deg C or -70 deg Cfor long term storage. Avoid repeated freeze/thaw cycles.
OfficialSymbol: ARL6
Gene Name: ARL6 ADP-ribosylation factor-like 6 [ Homosapiens ]
Synonyms: ARL6;ADP-ribosylation factor-like 6; BBS3; RP55; MGC32934; Bardet-Biedl syndrome 3protein; OTTHUMP00000214308; OTTHUMP00000214309; OTTHUMP00000214310;ADP-ribosylation factor-like protein 6
Gene ID: 84100
mRNA Refseq: NM_032146
Protein Refseq: NP_115522
MIM: 608845
UniProt ID: Q9H0F7
Chromosome Location: 3q11.2
Function: GTP binding; metalion binding; nucleotide binding; phospholipid binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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