Recombinant Human Dynein, Light Chain, LC8-Type 2, His-tagged


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Recombinant Human Dynein, Light Chain, LC8-Type 2, His-tagged

DYNLL2 Related Products

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Cat. No. : DYNLL2-4997H
Product Overview : Recombinant humanDYNLL2 protein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography techniques.
Description : Dynein light chain2, cytoplasmic, also known DYNLL2, is a large protein complex composed of sixdistinct subunits and is responsible for most intracellular movement towardthe minus ends of microtubules. Dyneins are multisubunit, high molecularweight ATPases that interact with microtubules to generate force byconverting the chemical energy of ATP into the mechanical energy of movement.DYNLL2 is a highly conserved eukaryotic hub protein with dozens of bindingpartners and various functions beyond being a subunit of dynein and myosin Vamotor proteins.
Concentration : 1 mg/ml
Source : Human
Host : E. coli
Form : Supplied as a liquidin 20 mM Tris-HCl buffer, pH 8.0, containing 1 mM DTT, 30% glycerol and 0.2 MNaCl.
Purity : > 90% by SDS-PAGE
Molecular Mass : 12.5 kDa (109 aa),confirmed by MALDI-TOF.
Applications : SDS-PAGE
Storage : Store at 4 deg C forshort term storage (1/2 weeks). Aliquot and store at -20 deg C or -70 deg Cfor long term storage. Avoid repeated freeze/thaw cycles.
OfficialSymbol : DYNLL2
nullValue_other :
Functioncytoskeletal proteinbinding; motor activity
../2012-03-04-04-00-34unProcess/DYNLL2-4997HDYNLL2, His-tagged(Human).pdfPDBrendering based on 1cmi. :

Gene Name : DYNLL2 dynein, light chain,LC8-type 2 [ Homo sapiens ]
Synonyms : DYNLL2; dynein,light chain, LC8-type 2; Dlc2; DNCL1B; RSPH22; MGC17810; dynein light chain2, cytoplasmic; DLC8b; radial spoke 22 homolog; 8 kDa dynein light chain b;radial spoke 22 homolog (Chlamydomonas); Dynein light chain 2, cytoplasmic;Dynein light chain LC8-type 2; DLC2
Gene ID : 140735
mRNA Refseq : NM_080677
Protein Refseq : NP_542408
MIM : 608942
UniProt ID : Q96FJ2
Chromosome Location : 17q22
Pathway : Activation ofBH3-only proteins; Activation of BMF and translocation to mitochondria;Apoptosis; Intrinsic Pathway for Apoptosis; Vasopressin-regulated waterreabsorption
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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