Recombinant Human Vesicular, Overexpressed In Cancer, Prosurvival Protein 1, His-tagged VOPP1-5155H

Recombinant Human Vesicular, Overexpressed In Cancer, Prosurvival Protein 1, His-tagged

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Recombinant Human Vesicular, Overexpressed In Cancer, Prosurvival Protein 1, His-tagged

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Cat. No. : VOPP1-5155H
Product Overview : Recombinant human VOPP1 protein,fused to His-tag at N-terminus, was expressed in E. coli and purified byusing conventional chromatography techniques.
Description : Vesicular, overexpressed in cancer,prosurvival protein 1(VOPP1), also known as Glioblastoma-amplified secretedprotein (GASP), has been previously shown to be over-expressed in humanglioblastoma multiforme and squamous cell carcinoma. VOPP1 is a key regulatorof NF-kappaB signaling, and that high-level, amplification-mediated VOPP1expression, such as that occurring in tumors with amplified EGFR, couldcontribute to resistance to apoptosis.
Concentration : 0.5 mg/ml
Source : Human
Host : E.coli
Form : Supplied as aliquid in 20mM Tris-HCl buffer, pH 8.0, containing 1mM DTT, 30% glycerol and0.2M NaCl.
Purity : > 90% by SDS - PAGE
Sequence : 82-172 amino acids: MGSSHHHHHHSSGLVPRGSH MRRRMYPPPL IEEPAFNVSY TRQPPNPGPG AQQPGPPYYT DPGGPGMNPV GNSMAMAFQVPPNSPQGSVA CPPPPAYCNT PPPPYEQVVK AK
Molecular Mass : 12 kDa (112aa), confirmed by MALDI-TOF
Applications : SDS-PAGE
Storage : Store at 4 deg Cfor short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70deg C for long term storage. Avoid repeated freeze/thaw cycles.
OfficialSymbol : VOPP1
Gene Name : VOPP1 vesicular, overexpressed in cancer, prosurvivalprotein 1 [ Homo sapiens ]
Synonyms : VOPP1; vesicular,overexpressed in cancer, prosurvival protein 1; ECOP; GASP; FLJ20532;DKFZp564K0822; vesicular,overexpressed in cancer, prosurvival protein 1; OTTHUMP00000209214; OTTHUMP00000209217;OTTHUMP00000209218; OTTHUMP00000209221; Glioblastoma-amplified secretedprotein; EGFR-coamplified and overexpressed protein
Gene ID : 81552
mRNA Refseq : NM_030796
Protein Refseq : NP_110423
MIM : 611915
UniProt ID : Q96AW1
Chromosome Location : 7p11.2
Function : signaltransducer activity

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