"VOPP1" Related Products

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Recombinant Human Vesicular, Overexpressed In Cancer, Prosurvival Protein 1, His-tagged

Cat. No.: VOPP1-5155H
Product Overview: Recombinant human VOPP1 protein,fused to His-tag at N-terminus, was expressed in E. coli and purified byusing conventional chromatography techniques.
Description: Vesicular, overexpressed in cancer,prosurvival protein 1(VOPP1), also known as Glioblastoma-amplified secretedprotein (GASP), has been previously shown to be over-expressed in humanglioblastoma multiforme and squamous cell carcinoma. VOPP1 is a key regulatorof NF-kappaB signaling, and that high-level, amplification-mediated VOPP1expression, such as that occurring in tumors with amplified EGFR, couldcontribute to resistance to apoptosis.
Concentration: 0.5 mg/ml
Source: Human
Host: E.coli
Form: Supplied as aliquid in 20mM Tris-HCl buffer, pH 8.0, containing 1mM DTT, 30% glycerol and0.2M NaCl.
Purity: > 90% by SDS - PAGE
Sequence: 82-172 amino acids: MGSSHHHHHHSSGLVPRGSH MRRRMYPPPL IEEPAFNVSY TRQPPNPGPG AQQPGPPYYT DPGGPGMNPV GNSMAMAFQVPPNSPQGSVA CPPPPAYCNT PPPPYEQVVK AK
Molecular Mass: 12 kDa (112aa), confirmed by MALDI-TOF
Applications: SDS-PAGE
Storage: Store at 4 deg Cfor short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70deg C for long term storage. Avoid repeated freeze/thaw cycles.
OfficialSymbol: VOPP1
Gene Name: VOPP1 vesicular, overexpressed in cancer, prosurvivalprotein 1 [ Homo sapiens ]
Synonyms: VOPP1; vesicular,overexpressed in cancer, prosurvival protein 1; ECOP; GASP; FLJ20532;DKFZp564K0822; vesicular,overexpressed in cancer, prosurvival protein 1; OTTHUMP00000209214; OTTHUMP00000209217;OTTHUMP00000209218; OTTHUMP00000209221; Glioblastoma-amplified secretedprotein; EGFR-coamplified and overexpressed protein
Gene ID: 81552
mRNA Refseq: NM_030796
Protein Refseq: NP_110423
MIM: 611915
UniProt ID: Q96AW1
Chromosome Location: 7p11.2
Function: signaltransducer activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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