Native Human Chorionic Gonadotropin, Beta Polypeptide


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Native Human Chorionic Gonadotropin, Beta Polypeptide

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Cat. No. : CGB-1850H
Product Overview : Native human CGB was expressedin Human Urine. Native Human Chorionic Gonadotropin, beta subunit.
Description : CGB is a glycoprotein hormoneproduced during pregnancy that is made by the developing embryo afterconception and later by the syncytiotrophoblast (part of the placenta). Sometumors make this hormone, measured elevated levels when the patient is notpregnant can lead to a cancer diagnosis. However, it is not known whetherthis production is a contributing cause or an effect of tumorigenesis. Thepituitary analog of CGB, known as luteinizing hormone (LH), is produced inthe pituitary gland of males and females of all ages.
Form : Lyophilized powder
Formulation : Lyophilized from50mM Ammonium Bicarbonate.
Source : Human Urine
Reconstitution : Reconstitute usingneutral pH buffer of choice. Avoid extreme high and low pH.
Molecular Weight : Approximately 22 kDa
Purity : ≥98% by SDS-PAGE
Grade : High Purity
Activity : 1mg/mg by Absorbanceat 280 nm
Certification : The material testednegative for anti-HIV-1/2, anti-HCV and HBsAg by FDA approvedmethods.
Storage : -2°C to -8°C forshort term storage, -20°C for long term storage after reconstitution. Productis stable for five years from date of delivery. Avoid freeze/thaw cycles.
Pathways : Glycoproteinhormones; Metabolism; Metabolism of amino acids and derivatives; Peptidehormone biosynthesis
PDBrendering based on 1hcn. :

Gene Name : CGB chorionic gonadotropin, betapolypeptide [ Homo sapiens ]
Official Symbol : CGB
Synonyms : CGB; chorionic gonadotropin, beta polypeptide; CGB3; CGB5; CGB7;CGB8; hCGB; choriogonadotropinsubunit beta; CG-beta; chorionic gonadotropin beta chain; chorionicgonadotrophin chain beta; chorionic gonadotropin beta subunit; chorionicgonadotropin beta 3 subunit; Choriogonadotropin subunit beta
Gene ID : 1082
mRNA Refseq : NM_000737
Protein Refseq : NP_000728
MIM : 118860
UniProt ID : P01233
Chromosome Location : 19q13.3
Function : hormoneactivity

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