Recombinant Human Annexin A1, T7-tagged ANXA1-5277H

Recombinant Human Annexin A1, T7-tagged

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Recombinant Human Annexin A1, T7-tagged

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Cat. No. : ANXA1-5277H
Product Overview : Recombinant HumanANXA1 (aa 1-346) was expessed in E. coli including a His tag. Its molecularweight is 41430 Dalton.
Description : ANXA1 belongs to a familyof Ca(2+)-dependent phospholipid binding proteins which have a molecularweight of approximately 35,000 to 40,000 and are preferentially located onthe cytosolic face of the plasma membrane. ANXA1 protein has an apparentrelative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity.Since phospholipase A2 is required for the biosynthesis of the potentmediators of inflammation, prostaglandins and leukotrienes, ANXA1 may havepotential anti-inflammatory activity.
Source : E. coli
Species : Human
Form : Liquid in 20 mMTris-HCl + 0.5 M NaCl + 100 mM imidazole + 1 mM 2-mercaptoethanol, pH 8.
Molecular Weight : 41.43 kDa
Applications : ELISA; Western Blot;Antibody Production; Protein array
OfficialSymbol : ANXA1
PDB rendering basedon 1ain. :

Gene Name : ANXA1 annexin A1 [ Homosapiens ]
Synonyms : ANXA1; annexin A1;ANX1; LPC1; Annexin A1; Annexin-1; Annexin I; Lipocortin I; Calpactin II;Chromobindin-9; p35; Phospholipase A2 inhibitory protein; OTTHUMP00000021475;OTTHUMP00000021474; annexin A1; annexin I (lipocortin I); annexin-1;calpactin-2; lipocortin I; chromobindin-9; phospholipase A2 inhibitoryprotein; annexin A1; Calpactin-2
Gene ID : 301
mRNA Refseq : NM_000700
Protein Refseq : NP_000691
MIM : 151690
UniProt ID : P04083
Chromosome Location : 9q12-q21.2; 9q21.13
Pathway : Class A/1(Rhodopsin-like receptors); Formyl peptide receptors bind formyl peptides andmany other ligands; G alpha (i) signalling events; G alpha (q) signallingevents; GPCR downstream signaling; GPCR ligand binding; Peptideligand-binding receptors; Prostaglandin Synthesis and Regulation; SignalTransduction; Signaling by GPCR
Function : calciumion binding; calcium-dependent phospholipid binding; phospholipase A2inhibitor activity; phospholipase inhibitor activity; protein binding,bridging; receptor binding; structural molecule activity; phospholipidbinding; protein binding; protein homodimerization activity; single-strandedDNA binding; single-stranded RNA binding

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