Native Human Apolipoprotein B (including Ag(x) antigen)
Cat.No. : | APOB-613H |
Product Overview : | Native human APOBwas expressed in human plasma.Itsmolecular weight is 550000 Dalton. |
- Specification
- Gene Information
- Related Products
Cat. No. : | APOB-613H |
Description : | APOB is thedominant protein constituent of LDL. The concentration of Apo B in normalplasma is 90 mg per 100 ml. APOB is thought to stabilize lipid emulsions,serve as a cofactor and modulator of enzymatic reactions, manage export oflipids out of cells and direct lipids to target organs. APOB levels arepositively correlated with the risk of coronary disease. Apo B levels may bea more sensitive predictor of cardiovascular risk than LDL levels and do notinvolve fasting for accurate measurement. Two forms of Apo B exist: Apo B-100and Apo B-48. The first is found in VLDL and LDL and is produced by theliver. The second is found in chylomicrons and originates in the intestine.Prepared from fresh, non-frozen plasma shown to be non reactive for HbsAG,anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approvedtests. Add deionized water to original volume, aliquot and freeze unusedportion. |
Form : | Lyophilized powderin 0.01 M Sodium Deoxycholate, 0.05 M Sodium Carbonate, 0.05 M. |
Source : | Human plasm |
Concentration : | Lyophilized |
MolecularWeight : | 550 kDa |
Purity : | > 95 percent pureby SDS-PAGE |
Storage : | When stored at -80°Cproduct is stable for 3 years from date of delivery. Avoid repeatedfreeze-thaw cycles. |
OfficialSymbol : | APOB |
Gene Name : | APOB apolipoprotein B (includingAg(x) antigen) [ Homo sapiens ] |
Synonyms : | APOB; apolipoproteinB (including Ag(x) antigen); FLDB; LDLCQ4; apolipoprotein B-100; apoB-48;apoB-100; apo B-100; mutant Apo B 100; apolipoprotein B48; ApolipoproteinB-100; OTTHUMP00000115994; Apo B-48 |
Gene ID : | 338 |
mRNA Refseq : | NM_000384 |
Protein Refseq : | NP_000375 |
MIM : | 107730 |
UniProt ID : | P04114 |
Chromosome Location : | 2p24-p23 |
Pathway : | Cellsurface interactions at the vascular wall; Chylomicron-mediated lipidtransport; FOXA1 transcription factor network; Fat digestion and absorption;Formation of Platelet plug; LDL-mediated lipid transport; Lipoproteinmetabolism; Vitamin digestion and absorption; Platelet Activation; amb2Integrin signaling |
Function : | cholesteroltransporter activity; enzyme binding; heparin binding; lipid transporteractivity; low-density lipoprotein particle receptor binding; phospholipidbinding; protein heterodimerization activity |
Products Types
◆ Recombinant Protein | ||
APOB-1813H | Recombinant Human APOB Protein (28-127 aa), His-tagged | +Inquiry |
APOB-219H | Recombinant Human APOB Protein, His-tagged | +Inquiry |
APOB-218C | Recombinant Cattle APOB Protein, His-tagged | +Inquiry |
APOB-630M | Recombinant Mouse APOB Protein, His (Fc)-Avi-tagged | +Inquiry |
Apob-217R | Recombinant Rat Apob Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
APOB-1H | Native Human Apolipoprotein B | +Inquiry |
APOB-8037H | Native Human Plasma APOB | +Inquiry |
ApoB-3556H | Native Human ApoB | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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