Recombinant Human SRC protein, His-tagged

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Recombinant Human SRC protein, His-tagged

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Cat.No. : SRC-533H
Product Overview : Recombinant Human SRC fused with His tag at N-terminal was expressed in Insect cells.
Description : This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Source : Insect cells
Species : Human
Tag : His
Form : 25 mM Tris-HCl, pH 8.0, 69 mM NaCl, 1.35 mM KCl, 0.025% Tween-20, 125 mM imidazole, 50% glycerol, and 3 mM DTT
Bio-activity : 205 pmol/min/μg
Molecular Mass : 60.5 kDa
Purity : >85%
Applications : Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Storage : >6 months at –80 centigrade. Avoid freeze/thaw cycles.
Concentration : 1.2 mg/ml
Figure :

Publication :
Gene Name : SRC SRC proto-oncogene, non-receptor tyrosine kinase [ Homo sapiens ]
Official Symbol : SRC
Synonyms : ASV; SRC1; THC6; c-SRC; p60-Src; proto-oncogene c-Src; protooncogene SRC, Rous sarcoma; tyrosine kinase pp60c-src; tyrosine-protein kinase SRC-1; v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
Gene ID : 6714
mRNA Refseq : NM_005417
Protein Refseq : NP_005408
MIM : 190090
UniProt ID : P12931
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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