"ADIPOQ" Related Products

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Recombinant Human Adiponectin, C1Q And Collagen Domain Containing

Cat. No.: ADIPOQ-1849H
Product Overview: Recombinant human ADIPOQcontains 145 amino acids corresponding to the C-terminal globular domain ofADIPOQ. It is expressed and secreted exclusively by adipose tissue.
Description: This protein possesses unique pharmacologicalproperties for regulation of body weight and lipid metabolism. It is a keycomponent in controlling energy homeostasis. Recently, ADIPOQ has been shownto inhibit the proliferation of myelomonocytic progenitors.
Source: E. coli
Species: Human
Molecular Weight: 16.6 kDa
Form: Lyophilized from 10mM Tris, pH 9.2 + 0.05% Sarcosyl + 0.75 mM DTT.
Purity: > 98% asdetermined by SDS-PAGE analysis.
Endotoxin Level: < 0.1 ng/µg ofADIPOQ
Biological Activity: Determined by itsability to inhibit the proliferation of mouse myeloid cell lines M1. The ED50is < 1-3 µg/ml.
Reconstitution: Centrifuge vialprior to opening. First add sterile distilled water to the vial to fully solubilizethe protein to a concentration of 1.0 mg/ml. After complete solubilization ofthe protein, it can be further diluted to other aqueous solutions.
Storage: Store lyophilizedprotein at -20°C to -80°C. Reconstituted protein is stable for 1 week at2-4°Cor in working aliquots at -20°C for longer storage. Avoid repeatedfreeze-thaw cycles.
OfficialSymbol: ADIPOQ
Gene Name: ADIPOQ adiponectin, C1Q andcollagen domain containing [ Homo sapiens ]
Synonyms: ADIPOQ; adiponectin,C1Q and collagen domain containing; ACDC; apM1; ADPN; APM1; APM-1; apM-1;GBP28; ACRP30; ADIPQTL1; adiponectin; AdipoQ; Gelatin-binding protein;OTTHUMP00000210047; OTTHUMP00000210048; gelatin-binding protein 28; adiposespecific collagen-like factor; 30 kDa adipocyte complement-related protein;adipocyte complement-related 30 kDa protein; adipose most abundant genetranscript 1 protein; adipocyte, C1Q and collagen domain containing
Gene ID: 9370
mRNA Refseq: NM_004797
Protein Refseq: NP_004788
MIM: 605441
UniProt ID: Q15848
Chromosome Location: 3q27
Pathway: Adipocytokinesignaling pathway; Adipogenesis; Developmental Biology; PPAR signalingpathway; Transcriptional Regulation of White Adipocyte Differentiation; TypeII diabetes mellitus
Function: cytokine activity;eukaryotic cell surface binding; hormone activity; identical protein binding;protein binding; protein homodimerization activity; receptor binding; sialicacid binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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