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Active Recombinant Human TSHB protein

Cat.No. : TSHB-105H
Product Overview : Recombinant Human TSHB(Phe21-Val138)&TSH alpha(Ala25-Ser116) was expressed in CHO.
  • Specification
  • Gene Information
  • Related Products
Source : CHO
Species : Human
Predicted N Terminal : Ala25 (TSH alpha ) & Phe21 (TSH beta )
Form : Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Bio-activity : Measured by its ability to induce cAMP accumulation in HEK293 human embryonic kidney cells transfected with human TSH R. Morgenthaler, N.G. et al. (1998) Horm. Metab. Res. 30:162. The ED50 for this effect is typically 0.25-1.5 ng/mL.
Molecular Mass : Predicted Molecular Mass: 10.2 (TSH alpha ), 13.5 (TSH beta ) kDa;
SDS-PAGE: 15-29 kDa, reducing conditions.
Endotoxin : <1.0 EU per 1 μg of the protein by the LAL method.
Purity : >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution : Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Gene Name : TSHB thyroid stimulating hormone, beta [ Homo sapiens ]
Official Symbol : TSHB
Synonyms : TSHB; thyroid stimulating hormone, beta; thyrotropin subunit beta; thyrotropin beta chain; thyrotropin beta subunit; thyroid-stimulating hormone subunit beta; TSH-B; TSH-BETA;
Gene ID : 7252
mRNA Refseq : NM_000549
Protein Refseq : NP_000540
MIM : 188540
UniProt ID : P01222

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there specific populations or conditions where TSHB protein assessment is particularly important? 03/09/2023

TSHB protein assessment is crucial in pregnant women, as thyroid function is vital for fetal development, and abnormalities can impact both the mother and the baby.

Can TSHB protein assessment be part of routine health check-ups? 04/19/2021

Yes, measuring TSHB protein levels is often included in routine thyroid function tests during health check-ups.

Can TSHB protein levels be indicative of autoimmune thyroid diseases? 03/08/2019

Yes, elevated TSHB levels may be associated with autoimmune thyroid diseases like Hashimoto's thyroiditis or Graves' disease.

How does the TSHB protein contribute to the management of thyroid cancer? 03/19/2017

TSHB protein levels are monitored to help manage thyroid cancer patients, especially after thyroidectomy, to ensure that thyroid-stimulating hormone levels are within a target range.

Are there advancements in technology or methods for measuring TSHB levels in clinical settings? 06/06/2016

Yes, advancements include highly sensitive immunoassays and molecular techniques that enhance the accuracy and efficiency of TSHB protein measurement.

Customer Reviews (3)

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Reviews
08/25/2021

    Researchers can feel confident in the reliability and efficacy of the TSHB protein and rely on the manufacturer's expertise to navigate any challenges that may arise during their trials.

    07/07/2019

      The manufacturer's commitment to excellence is evident through their provision of excellent technical support, which can prove vital in troubleshooting any experimental challenges or addressing specific research questions related to the protein.

      10/08/2017

        the TSHB protein's quality and suitability for experimental needs, combined with the manufacturer's excellent technical support, create a valuable partnership that enhances research outcomes.

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