Native Human Oxytocin, Prepropeptide


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Native Human Oxytocin, Prepropeptide

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Cat. No. : OXT-5360H
Product Overview : Native human OXT is synthetic.
Description : HumanOXT (Pitocin/Syntocinon) stimulates uterine smooth muscle contractions indirectlyand stimulates the mammary glands to increase lactation without increasingthe production of milk.
Form : Lyophilized from aconcentrated (1 mg/ml) solution in water containing no additives.
Source : Synthetic
Appearance : Sterile FilteredWhite lyophilized (freeze-dried) powder.
Sequence : Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2.
Purity : Greater than 98.0%as determined by: Analysis by RP-HPLC and Mass Spectral Analysis (MALDI-TOFexhibits correct MW).
Storage : Lyophilized Oxytocinalthough stable at room temperature for 3 weeks, should be stored desiccatedbelow -18°C. Upon reconstitution Oxytocin should be stored at 4°C between 2-7days and for future use below -18°C. For long term storage it is recommendedto add a carrier protein (0.1% HSA or BSA). Avoid freeze-thaw cycles.
Pathways : Class A/1(Rhodopsin-like receptors); G alpha (q) signalling events; GPCR downstreamsignaling; Myometrial Relaxation and Contraction Pathways; Peptideligand-binding receptors; Signal Transduction; Signaling by GPCR;Vasopressin-like receptors
Gene Name : OXT oxytocin, prepropeptide [ Homosapiens ]
Official Symbol : OXT
Synonyms : OXT; oxytocin, prepropeptide;OT; OT-NPI; MGC126890; MGC126892; oxytocin-neurophysin 1; neurophysin I;OTTHUMP00000030079; oxytocin, prepro- (neurophysin I); oxytocin-neurophysinI, preproprotein
Gene ID : 5020
mRNA Refseq : NM_000915
Protein Refseq : NP_000906
MIM : 167050
UniProt ID : P01178
Chromosome Location : 20p13
Function : neurohypophysealhormone activity; oxytocin receptor binding

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