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Native Human Gamma-Glutamyltransferase 1

Cat. No.: GGT1-5353H
Product Overview: Native Human GGT1 isprepared from Human Liver.
Description: Theenzyme catalyzes the transfer of the GGT1 to a variety of amino acids anddipeptide acceptors. The enzyme is composed of a heavy chain and a lightchain, which are derived from a single precursor protein, and is present intissues involved in absorption and secretion. The GGT1 is useful in thedetection of liver disease, obstructive jaundice, cholangitis, infectioushepatitus, and cholecystitis. It can also be used to detect diseases of thekidney and to differentiate liver or bile duct (hepatobiliary) disorders frombone disease.
Form: Ammonia SulfateSuspension
Source: Human Liver
Concentration: > 2 mg/ml
Biological Activity: One unit willcatalyze the transfer of one micromole of the glutamyl moiety fromgamma-glutamyl-p-nitroanilide hydrochloride (gamma-GPNA-HCl) to glycylglycineat 37oC.Measured at 405 nm as directly proportional formation of p-nitroaniline.
Endotoxin Level: < 0.1 ng/ug ofprotein
Specific Activity: > 50 U/mg proteinat 37oC
Storage: Store at -2-4oC. Stablefor 1 year.
Pathways: Arachidonic acid metabolism;Cyanoamino acid metabolism; Eicosanoid Synthesis; Glutathione metabolism;Metabolic pathways; Selenium Pathway; Taurine and hypotaurine metabolism;gamma-glutamyl cycle
Gene Name: GGT1gamma-glutamyltransferase 1 [ Homo sapiens ]
Official Symbol: GGT1
Synonyms: GGT1; gamma-glutamyltransferase1; GGT; GTG; CD224;D22S672; D22S732; MGC96892; MGC96904; MGC96963; GGT1;gamma-glutamyltranspeptidase1; glutamyl transpeptidase;gamma-glutamyltranspeptidase; CD224 antigen gamma-glutamyltransferase 1
Gene ID: 2678
mRNA Refseq: NM_001032364
Protein Refseq: NP_001027536
MIM: 612346
UniProt ID: P19440
Chromosome Location: 22q11
Function: acyltransferase activity;gamma-glutamyltransferase activity; protein binding; transferase activity

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