Recombinant Human Tumor Necrosis Factor Receptor Superfamily, Member 13C


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Recombinant Human Tumor Necrosis Factor Receptor Superfamily, Member 13C

TNFRSF13C Related Products

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Cat. No. : TNFRSF13C-5255H
Product Overview : Recombinant human TNFRSF13C is adisulfide-linked monomeric protein consisting of 76 amino acid residuesubunits. The molecule has a calculated molecular mass of approximately 9 kDaand migrates as an approximately 9 kDa protein under non-reducing andreducing conditions in SDS-PAGE.
Description : TNFRSF13C appears to be particularly important for the regulation of Bcell survival and maturation in the spleen, because A/WySnJ mice expressing adefective TNFRSF13C have disrupted B cell maturation, similar to that seen inBAFF-deficient mice.
Source : Human
Host : E. coli
Form : RecombinantTNFRSF13C was lyophilized from a 0.2 μm filtered solution in 2.5%glycine, 0.5% sucrose, 0.01% Tween80, 5 mM Glutamic acid, pH 4.5.
Purity : >95%, asdetermined by SDS-PAGE and HPLC.
Molecular Weight : 9 kDa.
Biological Activity : TheED(50) was determined by the ability to block BAFF induced survival ofsplenocyte cells, and was found to be in the range of 1.0-5.0 ug/ml.
Endotoxin : Less than 0.1 ng/µg (1EU/µg).
Reconstitution : A quick spin of thevial followed by reconstitution in distilled water to a concentration notless than 0.1 mg/ml. This solution can then be diluted into other buffers.
Storage : The lyophilizedprotein is stable for at least 2 years from date of receipt at -20°C. Uponreconstitution, this cytokine can be stored in working aliquots at 2°C - 8°Cfor one month, or at -20°C for six months, with a carrier protein withoutdetectable loss of activity. Avoid repeated freeze/thaw cycles.
OfficialSymbol : TNFRSF13C
Pathways : Cytokine-cytokine receptorinteraction
PDBrendering based on 1oqe. :

Gene Name : TNFRSF13C tumor necrosisfactor receptor superfamily, member 13C [ Homo sapiens ]
Synonyms : TNFRSF13C; tumor necrosisfactor receptor superfamily, member 13C; CD268; MGC138235; BAFF receptor;OTTHUMP00000028746; B cell-activating factor receptor; BAFF-R; BAFFR; BR3;BLyS receptor 3; CD268 antigen; tumor necrosis factor receptor superfamily,member 13C
Gene ID : 115650
mRNA Refseq : NM_052945
Protein Refseq : NP_443177
MIM : 606269
UniProt ID : Q5H8V1
Chromosome Location : 22q13.1-q13.31
Function : receptor activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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