Recombinant Human Annexin A3, His-tagged ANXA3-5260H

Recombinant Human Annexin A3, His-tagged


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Recombinant Human Annexin A3, His-tagged

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Cat. No. : ANXA3-5260H
Product Overview : Recombinanthuman ANXA3 was expressed in E.coli with an N-terminal Histag.
Description : AnnexinIII (ANXA3), otherwise known as Lipocortin III, is a calcium-dependentphospholipid-binding protein and member of the annexin family, which acts asan inhibitor of phospholipase A2, and is involved in the cleavage of inositol1, 2 cyclic phosphate to form inositol 1 phosphate. Studies have shown thatquantification of ANXA3 in patient urine can be used as a novel non-invasivebiomarker for prostatic cancer, complementary to prostate specific antigen.
Form : Purified recombinantprotein-liquid.
Application : ELISA; West Blotting
Preparation : Purified recombinant6x His-tagged ANXA3 expressed in E.coli.
Buffer Solution : Phosphatebuffered saline.
Molecular Weight : 39.5 kD(351 amino acid residues with tag).
Concentration : 0.5mg/ml
Storage : Store at -70oC.Storage in frost-free freezers is not recommended. This product should bestored undiluted. Avoid repeated freezing and thawing as this may denaturethe antibody. Should this product contain a precipitate we recommendmicrocentrifugation before use.
Pathways : ProstaglandinSynthesis and Regulation
PDB rendering based on 1aii. :

Gene Name : ANXA3 annexin A3 [ Homo sapiens ]
Official Symbol : ANXA3
Synonyms : ANXA3;annexin A3;ANX3; annexinA3; PAP-III; annexin-3; lipocortin III; OTTHUMP00000160701;OTTHUMP00000219237; OTTHUMP00000219238; 35-alpha calcimedin; calcimedin35-alpha; Annexin III (lipocortin III); placental anticoagulant protein III;inositol 1,2-cyclic phosphate 2-phosphohydrolase; annexin III (lipocortinIII, 1,2-cyclic-inositol-phosphate phosphodiesterase, placental anticoagulantprotein III, calcimedin 35-alpha)
Gene ID : 306
mRNA Refseq : NM_005139
Protein Refseq : NP_005130
MIM : 106490
UniProt ID : P12429
Chromosome Location : 4q21.21
Function : calcium ion binding;calcium-dependent phospholipid binding; phospholipase A2 inhibitor activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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