Recombinant Human Annexin A3, His-tagged ANXA3-5260H

Recombinant Human Annexin A3, His-tagged

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Recombinant Human Annexin A3, His-tagged

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Cat. No. : ANXA3-5260H
Product Overview : Recombinanthuman ANXA3 was expressed in E.coli with an N-terminal Histag.
Description : AnnexinIII (ANXA3), otherwise known as Lipocortin III, is a calcium-dependentphospholipid-binding protein and member of the annexin family, which acts asan inhibitor of phospholipase A2, and is involved in the cleavage of inositol1, 2 cyclic phosphate to form inositol 1 phosphate. Studies have shown thatquantification of ANXA3 in patient urine can be used as a novel non-invasivebiomarker for prostatic cancer, complementary to prostate specific antigen.
Form : Purified recombinantprotein-liquid.
Application : ELISA; West Blotting
Preparation : Purified recombinant6x His-tagged ANXA3 expressed in E.coli.
Buffer Solution : Phosphatebuffered saline.
Molecular Weight : 39.5 kD(351 amino acid residues with tag).
Concentration : 0.5mg/ml
Storage : Store at -70oC.Storage in frost-free freezers is not recommended. This product should bestored undiluted. Avoid repeated freezing and thawing as this may denaturethe antibody. Should this product contain a precipitate we recommendmicrocentrifugation before use.
Pathways : ProstaglandinSynthesis and Regulation
PDB rendering based on 1aii. :

Gene Name : ANXA3 annexin A3 [ Homo sapiens ]
Official Symbol : ANXA3
Synonyms : ANXA3;annexin A3;ANX3; annexinA3; PAP-III; annexin-3; lipocortin III; OTTHUMP00000160701;OTTHUMP00000219237; OTTHUMP00000219238; 35-alpha calcimedin; calcimedin35-alpha; Annexin III (lipocortin III); placental anticoagulant protein III;inositol 1,2-cyclic phosphate 2-phosphohydrolase; annexin III (lipocortinIII, 1,2-cyclic-inositol-phosphate phosphodiesterase, placental anticoagulantprotein III, calcimedin 35-alpha)
Gene ID : 306
mRNA Refseq : NM_005139
Protein Refseq : NP_005130
MIM : 106490
UniProt ID : P12429
Chromosome Location : 4q21.21
Function : calcium ion binding;calcium-dependent phospholipid binding; phospholipase A2 inhibitor activity

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