"DCTPP1" Related Products

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Recombinant Human DCTP Pyrophosphatase 1, His-tagged

Cat. No.: DCTPP1-1381H
Product Overview: Recombinanthuman DCTPP1 protein, fused to His-tag at N-terminus, was expressedin E.coli and purified by conventional chromatography.
Description: DCTPP1,also known as dCTP pyrophosphatase 1, contains an epilepsy-associated repeat(EAR) domain that is predicted to participate in protein-proteininteractions, most likely involved in ligand recognition. This proteinfunctions to hydrolyze abnormal nucleotide triphosphates (NTPs) in cancercells that, if unregulated, could be incorporated into nascent DNA or RNA.Recombinant human DCTPP1 protein, fused to His-tag at N-terminus, wasexpressed in E.coli and purified by using conventional chromatography.
Form: Liquid. 20mMTris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl.
Molecular Weight: 21.2 kDa (194aa),confirmed by MALDI-TOF.
Purity: > 90% by SDS-PAGE
Concentration: 0.5 mg/ml(determined by Bradford assay)
Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MGSHMSVAGG EIRGDTGGED TAAPGRFSFS PEPTLEDIRR LHAEFAAERDWEQFHQPRNL LLALVGEVGE LAELFQWKTD GEPGPQGWSP RERAALQEELSDVLIYLVAL AARCRVDLPL AVLSKMDINR RRYPAHLARS SSRKYTELPH GAISEDQAVG PADIPCDSTGQTST
Storage: Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: DCTPP1 dCTP pyrophosphatase 1 [Homo sapiens ]
Official Symbol: DCTPP1
Synonyms: DCTPP1;dCTP pyrophosphatase 1; CDA03; RS21C6; MGC5627; XTP3TPA; dCTPpyrophosphatase 1; dCTPase 1; OTTHUMP00000163253; XTP3-transactivated proteinA; deoxycytidine-triphosphatase 1; XTP3-transactivated gene A protein
Gene ID: 79077
mRNA Refseq: NM_024096
Protein Refseq: NP_077001
UniProt ID: Q9H773
Chromosome Location: 16p11.2
Function: dCTP diphosphataseactivity; hydrolase activity; magnesium ion binding; nucleoside-triphosphatediphosphatase activity; nucleotide binding; pyrimidine deoxyribonucleotidebinding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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