Native Bovine Pancreatic Trypsin Inhibitor


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Native Bovine Pancreatic Trypsin Inhibitor

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Cat. No. : PTI-1900B
Product Overview : Native Bovine is purifiedBovine lung.
Description : PTI is a natural proteinase inhibitorpolypeptide consisting of fifty-eight amino acids arranged in a single polypeptidechain, cross-linked by three disulfide bridges and having a MW of 6.512 kDa.
Source : Bovine lung
Species : Bovine
Form : Aprotinin (1 mg/ml)was lyophilized with no additives.
Purity : Greater than 98.0%as determined by: Analysis by RP-HPLC, anion-exchange FPLC, and analysis byreducing and non-reducing SDS-PAGE Silver Stained gel.
Endotoxin : Less than 0.1 ng/ug(1 EU/ug) of PTI.
Biological activity : PTI activitywas found to be 6 x 10⁶ IU/mg.
Storage : LyophilizedAprotinin although stable at room temperature for 3 weeks, should be storeddesiccated below -18°C. Upon reconstitution Aprotinin should be stored at 4°Cbetween 2-7 days and for future use below -18°C. For long term storage it isrecommended to add a carrier protein (0.1% HSA or BSA). Avoid freeze-thawcycles.
OfficialSymbol : PTI
Gene Name : PTI pancreatic trypsininhibitor [ Bos taurus ]
Synonyms : PTI; pancreatictrypsin inhibitor; BPI; BPTI; pancreatic trypsin inhibitor; aprotinin; basicprotease inhibitor
Gene ID : 404172
mRNA Refseq : NM_001001554
Protein Refseq : NP_001001554
UniProt ID : P00974
Chromosome Location : 13
Pathway : Axon guidance; Developmental Biology;Glypican 1 network; NCAM signaling for neurite out-growth; NCAM1interactions; Prion diseases
Function : peptidase inhibitor activity; potassiumchannel inhibitor activity; serine-type endopeptidase inhibitor activity

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