"TIE1" Related Products


Recombinant Human Tyrosine Kinase With Immunoglobulin-Like And EGF-Like Domains 1, Fc-tagged

Cat. No.: TIE1-1913H
Product Overview: Recombinant humansoluble TIE1 was fused with the Fc part of human IgG1.
Description: TIE1 and TIE2 comprisea receptor tyrosine kinase subfamily with unique structural characteristics:two immunoglobulin-like domains flanking three epidermal growth factor-likedomains and followed by three fibronectin type III-like repeats in theextracellular region and a split tyrosine kinase domain in the cytoplasmicregion.
Source: Insect cells
Species: Human
Form: Lyophilized
Purity: > 90% by SDS-PAGEand visualized by silver stain.
Molecular Weight: 250 kDa
Subunit: Glycosylated dimer
Endotoxin Level: < 0.1 ng per μgof sTIE-1/Fc.
Biological Activity: Since a ligand forTIE1 has not yet been identified, the recombinant protein was not tested forbiological activity.
Storage: Samples are stablefor 2-4 weeks at +4°C. sTIE-1/Fc should be stored in working aliquots at-20°C to -80°C. Avoid repeated freeze-thaw cycles.
OfficialSymbol: TIE1
Gene Name: TIE1 tyrosine kinase withimmunoglobulin-like and EGF-like domains 1 [ Homo sapiens ]
Synonyms: TIE1; tyrosinekinase with immunoglobulin-like and EGF-like domains 1; TIE; JTK14; tyrosine-proteinkinase receptor Tie-1; OTTHUMP00000008352; soluble TIE1 variant 1; solubleTIE1 variant 2; soluble TIE1 variant 3; soluble TIE1 variant 4; soluble TIE1variant 5; receptor tyrosine kinase; tyrosine kinase with immunoglobulin andepidermal growth factor homology domains 1; EC; Tyrosine-protein kinase receptor Tie-1
Gene ID: 7075
mRNA Refseq: NM_005424
Protein Refseq: NP_005415
MIM: 600222
UniProt ID: P35590
Chromosome Location: 1p34-p33
Function: ATP binding;nucleotide binding; protein binding; protein tyrosine kinase activity;receptor activity; transmembrane receptor protein tyrosine kinase activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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