Recombinant Human Geranylgeranyl Diphosphate Synthase 1, T7-tagged

• Cat.No.: GGPS1-825H
• Product Overview: Recombinant GGPS1 protein was expressed in E.coliwith T7-tag at the N-terminus. The molecular weight is 34871 Da

Specification

• Cat. No.: GGPS1-825H
• Description: GGPS1 geranylgeranyl diphosphate synthase 1 is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
• Sequences of amino acids: 1-300 aa
• Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3. 10mM DTT.
• Purity: 95%

Gene Information

• Gene Name: GGPS1 geranylgeranyl diphosphate synthase 1 [ Homo sapiens ]
• Synonyms: GGPPS; GGPPS1; GGPS1; geranylgeranyl pyrophosphate synthase; GGPPSase; GGPP synthase; OTTHUMP00000216161; OTTHUMP00000216162; OTTHUMP00000216163; OTTHUMP00000216164; geranylgeranyl diphosphate synthase 1; geranylgeranyl pyrophosphate synthase; Geranylgeranyl diphosphate synthase
• Gene ID: 9453
• mRNA Refseq: NM_001037277
• Protein Refseq: NP_001032354
• MIM: 606982
• UniProt ID: O95749
• Chromosome Location: 1q43
• Pathway: ECM-receptor interaction; Focal adhesion; Toll-like receptor signaling pathway; Integrin cell surface interactions; Signaling by PDGF
• Function: cytokine activity