Native Rat Ceruloplasmin


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Native Rat Ceruloplasmin

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Cat. No. : Cp-048R
Product Overview : Native Rat Cp is anapproximately 120 kDa monomeric serum protein that fuctions as a coppertransporter. It is a positive acute phase reactant, the levels of whichincrease significantly in mice in response to inflammation, tissue injury anddisease.
Description : Cp (orcaeruloplasmin) is a ferroxidase enzyme that in humans is encoded by the CPgene. Cp is the major copper-carrying protein in the blood, and in additionplays a role in iron metabolism. It was first described in 1948. Anotherprotein, hephaestin, is noted for its homology to ceruloplasmin, and alsoparticipates in iron and probably copper metabolism.
Form : Liquid in 20 mM TrisHCl, pH 7.5 + 1 mM EDTA.
Source : Rat Serum
Purity : > 90% by SDS-PAGE
Concentration : > 0.5 mg/mg
Storage : Stored at -20°C.Avoid repeated freeze-thaw cycles.
OfficialSymbol : Cp
Pathways : Porphyrin andchlorophyll metabolism
PDB rendering basedon 1kcw. :

Gene Name : Cp ceruloplasmin [ Rattus norvegicus]
Synonyms : Cp; ceruloplasmin;CERP; RATCERP; Ceruloplasmin; EC; Ferroxidase
Gene ID : 24268
mRNA Refseq : NM_012532
Protein Refseq : NP_036664
UniProt ID : P13635
Chromosome Location : 2q24
Function : chaperone binding;copper ion binding; ferroxidase activity; metal ion binding; oxidoreductaseactivity

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