"CDC42BPA" Related Products

Recombinant Human CDC42 Binding Protein Kinase Alpha (DMPK-like), His-tagged

Cat. No. : CDC42BPA-368H
Product Overview : Recombinanthuman CDC42BPA, catalytic domain (amino acids 1-473) with His Tag.
Description : Theprotein encoded by this gene is a member of the Serine/Threonine proteinkinase family. This kinase contains multiple functional domains. Its kinasedomain is highly similar to that of the myotonic dystrophy protein kinase(DMPK). This kinase also contains a Rac interactive binding (CRIB) domain,and has been shown to bind CDC42. It may function as a CDC42 downstreameffector mediating CDC42 induced peripheral actin formation, and promotingcytoskeletal reorganization. Multiple alternatively spliced transcriptvariants have been described, and the full-length nature of two of them hasbeen reported.
Source : Insectcells
Species : Human
Form : Liquid in50 mM Tris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2 mMDTT + 50% glycerol.
Molecular Weight : 58.7 kDa
Purity : ≥ 90% asdetermined by a Coomassie blue-stained SDS-PAGE gel.
Specific Activity : 179 nmoleof phosphate transferred to S6 peptide substrate (AKRRRLSSLRA) per minute permg of total protein at 30°C. Activity determined at a final protein concentrationof 3.33 ug/ml.
Storage : Stablefor 6 months in working aliquots at -80°C. Avoid repeated freeze-thaw cycles.
OfficialSymbol : CDC42BPA
Gene Name : CDC42BPACDC42 binding protein kinase alpha (DMPK-like) [ Homo sapiens ]
Synonyms : CDC42BPA;CDC42 binding protein kinase alpha (DMPK-like); MRCK; MRCKA; PK428;FLJ23347; KIAA0451; DKFZp686L1738; DKFZp686P1738; CDC42-bindingprotein kinase alpha (DMPK-like); OTTHUMP00000035727; OTTHUMP00000035728; OTTHUMP00000035729;OTTHUMP00000035730; OTTHUMP00000035731; OTTHUMP00000035732; OTTHUMP00000035733;Serine/threonine-proteinkinase MRCK alpha; EC; CDC42-binding protein kinasealpha; DMPK-like alpha; Myotonic dystrophy kinase-related CDC42-binding kinasealpha; ser-thr protein kinaserelated to the myotonic dystrophy protein kinase
Gene ID : 8476
mRNA Refseq : NM_003607
Protein Refseq : NP_003598
MIM : 603412
UniProt ID : Q5VT25
Chromosome Location : 1q42.11
Pathway : CDC42 signalingevents
Function : protein binding; ATPbinding; identical protein binding; magnesium ion binding; nucleotidebinding; protein serine/threoninekinase activity; small GTPase regulator activity

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.