"CDC42BPB" Related Products

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Recombinant Human CDC42 Binding Protein Kinase Beta, GST-His-tagged

Cat. No.: CDC42BPB-369H
Product Overview: Recombinanthuman CDC42BPB containing amino acids M1-H472, N-terminally fused toGST-HIS6-Thrombin cleavage site.
Description: This geneencodes a member of the serine/threonine protein kinase family. The encodedprotein contains a Cdc42/Rac-binding p21 binding domain resembling that ofPAK kinase. The kinase domain of this protein is most closely related to thatof myotonic dystrophy kinase-related ROK. Studies of the similar gene in ratsuggested that this kinase may act as a downstream effector of Cdc42 incytoskeletal reorganization.
Source: Sf9 cells
Species: Human
Form: Liquid in50 mM Tris-HCl, pH 8.0 + 100 mM NaCl + 5 mM DTT + 4 mM reduced glutathione +20% glycerol.
Molecular Weight: 84.4 kDa
Purity: Affinitypurified using GSH-agarose.
Specific Activity: 14 pmol/ugx min
Storage: Store in working aliquots at -80°C.Avoid repeated freeze-thaw cycles.
OfficialSymbol: CDC42BPB
Gene Name: CDC42BPBCDC42 binding protein kinase beta (DMPK-like) [ Homo sapiens ]
Synonyms: CDC42BPB;CDC42 binding protein kinase beta (DMPK-like); MRCKB; FLJ37601;FLJ44730; KIAA1124; DKFZp686H1431; CDC42-binding protein kinase beta(DMPK-like); Serine/threonine-proteinkinase MRCK beta; EC 2.7.11.1; CDC42-binding protein kinasebeta; CDC42BP-beta; DMPK-like beta; Myotonic dystrophy kinase-related CDC42-bindingkinase beta; MRCKbeta;myotonic dystrophy protein kinase-like beta; EC 2.7.11
Gene ID: 9578
mRNA Refseq: NM_006035
Protein Refseq: NP_006026
MIM: 614062
UniProt ID: Q9Y5S2
Chromosome Location: 14q32.3
Function: proteinkinase binding; ATP binding; magnesium ion binding; nucleotidebinding; protein serine/threoninekinase activity; small GTPase regulator activity; Rho GTPase binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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