||FOSB encodes a nuclear protein of 338amino acids which has 70% homology with c-Fos, exhibits similar kinetics ofexpression as c-Fos and forms heterodimers with both c-Jun and Jun B whichbind to TRE DNA response elements. Functional homologs of c-Fos and FOSBinclude Fra-1 and Fra-2 genes.
||FOSBis a protein that, in humans, is encoded by the FOSB gene. The Fos genefamily consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encodeleucine zipper proteins that can dimerize with proteins of the JUN family,thereby forming the transcription factor complex AP-1. As such, the FOSproteins have been implicated as regulators of cell proliferation,differentiation, and transformation.
||Recombinant Human FOSB protein(a.a.113-151) at 100 μg/ml in 50 mM Tris-Acetate + pH7.5 + 1 Mm EDTA +20%Glycerol.
||ELISA; Inhibition Assays; WesternBlotting
||Store vial at -20°C to -80°C. Whenstored at the recommended temperature, this protein is stable for 12 months.Please avoid freeze-thaw cycles.