Recombinant Human FBJ Murine Osteosarcoma Viral Oncogene Homolog B
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| Cat. No. : | FOSB-1230H |
| Product Overview : | FOSB encodes a nuclear protein of 338amino acids which has 70% homology with c-Fos, exhibits similar kinetics ofexpression as c-Fos and forms heterodimers with both c-Jun and Jun B whichbind to TRE DNA response elements. Functional homologs of c-Fos and FOSBinclude Fra-1 and Fra-2 genes. |
| Description : | FOSBis a protein that, in humans, is encoded by the FOSB gene. The Fos genefamily consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encodeleucine zipper proteins that can dimerize with proteins of the JUN family,thereby forming the transcription factor complex AP-1. As such, the FOSproteins have been implicated as regulators of cell proliferation,differentiation, and transformation. |
| Source : | E. coli |
| Species : | Human |
| Form : | Recombinant Human FOSB protein(a.a.113-151) at 100 μg/ml in 50 mM Tris-Acetate + pH7.5 + 1 Mm EDTA +20%Glycerol. |
| Application : | ELISA; Inhibition Assays; WesternBlotting |
| Storage : | Store vial at -20°C to -80°C. Whenstored at the recommended temperature, this protein is stable for 12 months.Please avoid freeze-thaw cycles. |
| OfficialSymbol : | FOSB |
| Gene Name : | FOSB FBJmurine osteosarcoma viral oncogene homolog B [ Homo sapiens ] |
| Synonyms : | FOSB; FBJ murine osteosarcoma viraloncogene homolog B; AP-1; G0S3; GOS3; GOSB; MGC42291;DKFZp686C0818; activator protein 1; oncogene FOS-B; protein fosB; G0/G1switch regulatory protein 3 |
| Gene ID : | 2354 |
| mRNA Refseq : | NM_001114171 |
| Protein Refseq : | NP_001107643 |
| MIM : | 164772 |
| UniProt ID : | P53539 |
| Chromosome Location : | 19q13.3 |
| Pathway : | Osteoclast differentiation; TGF-betaReceptor Signaling Pathway |
| Function : | protein dimerization activity; sequence-specific DNA binding;transcription factor activity; sequence-specific DNA binding transcriptionfactor activity; DNA binding |
◆ Recombinant Protein
| FOSB-4425H | Recombinant Human FOSB Protein, GST-tagged | +Inquiry |
| FOSB-12964H | Recombinant Human FOSB, GST-tagged | +Inquiry |
| FOSB-28107TH | Recombinant Human FOSB | +Inquiry |
| FOSB-1704Z | Recombinant Zebrafish FOSB | +Inquiry |
| FOSB-1303H | Recombinant HumanFOSB,GST-tagged,113-151aa | +Inquiry |
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◆ Lysates
| FOSB-6167HCL | Recombinant Human FOSB 293 Cell Lysate | +Inquiry |
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