| Cat. No. : |
FGFR2-5418H |
| Product Overview : |
Recombinant humanFGFR2 cytoplasmic domain (amino acids 403-822), His-tagged. No specialmeasures were taken to activate this kinase. |
| Description : |
This protein functions as amodifier of endothelial cell migration and proliferation, as well as anangiogenic factor. It acts as a mitogen for a variety of mesoderm- andneuroectoderm-derived cells in vitro, thus is thought to be involved inorganogenesis. Three alternatively spliced variants encoding differentisoforms have been described. The heparin-binding growth factors areangiogenic agents in vivo and are potent mitogens for a variety of cell typesin vitro. There are differences in the tissue distribution and concentrationof these 2 growth factors. |
| Source : |
Insect cells |
| Species : |
Human |
| MolecularWeight : |
52.1 kDa |
| Purity : |
≥ 90% as determinedby SDS-PAGE analysis |
| Specific Activity : |
2700nmole of phosphate transferred to poly [Glu,Tyr] 4:1 substrate per minute permg oftotalprotein at 30°C. Activity determined at a final protein concentration of 1μg/ml. |
| Storage : |
Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles. |
| OfficialSymbol : |
FGFR2 |
