Recombinant Human B Lymphoid Tyrosine Kinase, His-tagged
Cat.No. : |
BLK-5368H |
Product Overview : |
Recombinant HumanBLK with His Tag. BLK is a non-receptor tyrosine kinase that belongs to theSrc family of kinases. BLK plays an important role in B-cell activation. |
- Specification
- Gene Information
- Related Products
Cat. No. : |
BLK-5368H |
Description : |
Tyrosine-proteinkinase BLK also known as B lymphocyte kinase is an enzyme that in humans isencoded by the BLK gene. This gene encodes a nonreceptor tyrosine-kinase ofthe src family of proto-oncogenes that are typically involved in cellproliferation and differentiation. The protein has a role in B-cell receptorsignaling and B-cell development. |
Source : |
Insect cells |
Species : |
Human |
Form : |
Liquid in 50 mMTris, pH 7.5 + 100 mM NaCl + 0.1 mM EDTA + 0.05% NP-40 + 5 mM DTT + 50%glycerol. |
MolecularWeight : |
62.3 kDa |
Concentration : |
0.39 mg/ml |
Storage : |
Stable for 6 monthsat -80°C. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : |
BLK |
Pathways : |
Alpha-synucleinsignaling; B Cell Receptor Signaling Pathway; CXCR4-mediated signalingevents; Class I PI3K signaling events; EPHA forward signaling; Ephrin Breverse signaling; Focal Adhesion; Glypican 1 network; IL-7 SignalingPathway; PDGFR-beta signaling pathway; Regulation of p38-alpha and p38-beta;Signaling events mediated by PTP1B; Thromboxane A2 receptor signaling;Thromboxane A2 receptor signaling |
Gene Name : |
BLK B lymphoid tyrosine kinase [ Homosapiens ] |
Synonyms : |
BLK; Blymphoid tyrosine kinase; MODY11; MGC10442; tyrosine-proteinkinase Blk; p55-Blk; OTTHUMP00000115909; OTTHUMP00000229490; b lymphocytekinase; BLK nonreceptor tyrosine kinase; EC 2.7.10.2; Tyrosine-protein kinase Blk |
Gene ID : |
640 |
mRNA Refseq : |
NM_001715 |
Protein Refseq : |
NP_001706 |
MIM : |
191305 |
UniProt ID : |
P51451 |
Chromosome Location : |
8p23-p22 |
Function : |
ATP binding;non-membrane spanning protein tyrosine kinase activity; nucleotide binding;protein tyrosine kinase activity |
Products Types
Related Gene
BLK
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.