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Recombinant Human B Lymphoid Tyrosine Kinase, His-tagged

Cat.No. : BLK-5368H
Product Overview : Recombinant HumanBLK with His Tag. BLK is a non-receptor tyrosine kinase that belongs to theSrc family of kinases. BLK plays an important role in B-cell activation.
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Cat. No. : BLK-5368H
Description : Tyrosine-proteinkinase BLK also known as B lymphocyte kinase is an enzyme that in humans isencoded by the BLK gene. This gene encodes a nonreceptor tyrosine-kinase ofthe src family of proto-oncogenes that are typically involved in cellproliferation and differentiation. The protein has a role in B-cell receptorsignaling and B-cell development.
Source : Insect cells
Species : Human
Form : Liquid in 50 mMTris, pH 7.5 + 100 mM NaCl + 0.1 mM EDTA + 0.05% NP-40 + 5 mM DTT + 50%glycerol.
MolecularWeight : 62.3 kDa
Concentration : 0.39 mg/ml
Storage : Stable for 6 monthsat -80°C. Avoid repeated freeze-thaw cycles.
OfficialSymbol : BLK
Pathways : Alpha-synucleinsignaling; B Cell Receptor Signaling Pathway; CXCR4-mediated signalingevents; Class I PI3K signaling events; EPHA forward signaling; Ephrin Breverse signaling; Focal Adhesion; Glypican 1 network; IL-7 SignalingPathway; PDGFR-beta signaling pathway; Regulation of p38-alpha and p38-beta;Signaling events mediated by PTP1B; Thromboxane A2 receptor signaling;Thromboxane A2 receptor signaling
Gene Name : BLK B lymphoid tyrosine kinase [ Homosapiens ]
Synonyms : BLK; Blymphoid tyrosine kinase; MODY11; MGC10442; tyrosine-proteinkinase Blk; p55-Blk; OTTHUMP00000115909; OTTHUMP00000229490; b lymphocytekinase; BLK nonreceptor tyrosine kinase; EC 2.7.10.2; Tyrosine-protein kinase Blk
Gene ID : 640
mRNA Refseq : NM_001715
Protein Refseq : NP_001706
MIM : 191305
UniProt ID : P51451
Chromosome Location : 8p23-p22
Function : ATP binding;non-membrane spanning protein tyrosine kinase activity; nucleotide binding;protein tyrosine kinase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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