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Recombinant Mouse Calreticulin

Cat. No. : Calr-1185M
Product Overview : Recombinant mouseCalr full length protein.
Description : Calr also known as calregulin, CRP55, CaBP3,calsequestrin-like protein, and endoplasmic reticulum resident protein 60(ERp60) is a protein that in humans is encoded by the CALR gene. Calr is a multifunctional protein that binds Ca2+ ions (asecond messenger in signal transduction), rendering it inactive. The Ca2+ isbound with low affinity, but high capacity, and can be released on a signal(see inositol triphosphate). Calr is located in storage compartmentsassociated with the endoplasmic reticulum.
Source : E. coli
Species : Mouse
Form : Sterile filteredliquid in 50 mM Tris-Acetate, pH 7.5 + 1 mM EDTA + 20% glycerol.
Molecular Weight : 57 kDa
Concentration : 0.1 mg/ml
Endotoxin Level : < 0.1 ng/µg ofCALR
Storage : Stable for 1 year inworking aliquots at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
OfficialSymbol : Calr
PDB rendering basedon 1hhn. :

Gene Name : Calr calreticulin [ Musmusculus ]
Synonyms : Calr; calreticulin;CRT; SSA; CRTC; Calregulin; CRP55; RO; ERp60; grp60; cC1qR; HACBP; FLJ26680;Endoplasmic reticulum resident protein 60; OTTMUSP00000025211; endoplasmic reticulumresident protein 60; autoantigen Ro; Sicca syndrome antigen A (autoantigenRo; calreticulin)
Gene ID : 12317
mRNA Refseq : NM_007591
Protein Refseq : NP_031617
UniProt ID : P14211
Chromosome Location : 8 C3; 8 37.0 cM
Pathway : Activation ofChaperones by ATF6-alpha; Androgen Receptor Signaling Pathway; AndrogenReceptor Signaling Pathway; Calcium Regulation in the Cardiac Cell; Chagasdisease (American trypanosomiasis); Diabetes pathways; HTLV-I infection;Phagosome; Protein processing in endoplasmic reticulum; Unfolded ProteinResponse
Function : androgen receptorbinding; calcium ion binding; hormone binding; integrin binding; iron ionbinding; mRNA binding; metal ion binding; peptide binding; sugar binding;ubiquitin protein ligase binding; unfolded protein binding

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