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Recombinant Mouse Calreticulin

Cat. No.: Calr-1185M
Product Overview: Recombinant mouseCalr full length protein.
Description: Calr also known as calregulin, CRP55, CaBP3,calsequestrin-like protein, and endoplasmic reticulum resident protein 60(ERp60) is a protein that in humans is encoded by the CALR gene. Calr is a multifunctional protein that binds Ca2+ ions (asecond messenger in signal transduction), rendering it inactive. The Ca2+ isbound with low affinity, but high capacity, and can be released on a signal(see inositol triphosphate). Calr is located in storage compartmentsassociated with the endoplasmic reticulum.
Source: E. coli
Species: Mouse
Form: Sterile filteredliquid in 50 mM Tris-Acetate, pH 7.5 + 1 mM EDTA + 20% glycerol.
Molecular Weight: 57 kDa
Concentration: 0.1 mg/ml
Endotoxin Level: < 0.1 ng/µg ofCALR
Storage: Stable for 1 year inworking aliquots at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
OfficialSymbol: Calr
Gene Name: Calr calreticulin [ Musmusculus ]
Synonyms: Calr; calreticulin;CRT; SSA; CRTC; Calregulin; CRP55; RO; ERp60; grp60; cC1qR; HACBP; FLJ26680;Endoplasmic reticulum resident protein 60; OTTMUSP00000025211; endoplasmic reticulumresident protein 60; autoantigen Ro; Sicca syndrome antigen A (autoantigenRo; calreticulin)
Gene ID: 12317
mRNA Refseq: NM_007591
Protein Refseq: NP_031617
UniProt ID: P14211
Chromosome Location: 8 C3; 8 37.0 cM
Pathway: Activation ofChaperones by ATF6-alpha; Androgen Receptor Signaling Pathway; AndrogenReceptor Signaling Pathway; Calcium Regulation in the Cardiac Cell; Chagasdisease (American trypanosomiasis); Diabetes pathways; HTLV-I infection;Phagosome; Protein processing in endoplasmic reticulum; Unfolded ProteinResponse
Function: androgen receptorbinding; calcium ion binding; hormone binding; integrin binding; iron ionbinding; mRNA binding; metal ion binding; peptide binding; sugar binding;ubiquitin protein ligase binding; unfolded protein binding

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