"CAMK2A" Related Products


Recombinant Human CAMK2A, His-tagged

Cat. No. : CAMK2A-1186H
Product Overview : Recombinant humanfull length CAMK2A with His tag is expressed ininsect cells.
Description : CAMK2A is an enzyme thatin humans is encoded by the CAMK2A gene.The product of this gene belongs tothe Serine/Threonine protein kinases family, and to the Ca2+/calmodulin-dependentprotein kinases subfamily. Calcium signaling is crucial for several aspectsof plasticity at glutamatergic synapses. This enzyme is composed of fourdifferent chains: alpha, beta, gamma, and delta. The alpha chain encoded bythis gene is required for hippocampal long-term potentiation (LTP) andspatial learning.
Source : Insect cells
Species : Human
Form : Liquid in20 mM Tris, pH 7.5 + 100 mM NaCl + 0.5 mM EDTA + 0.05% NP-40 + 2 Mm DTT + 50%glycerol.
Molecular Weight : 56.8 kDa
Concentration : 0.34 mg/ml
Purity : ≥90%
Specific Activity : 7300nmole of phosphate transferred to autocamtide-2 per minute per mg of totalprotein at 30°C. Activity determined at a final protein concentration of 0.05ug/ml.
Storage : Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles.
OfficialSymbol : CAMK2A
PDB rendering basedon 1hkx. :

Gene Name : CAMK2Acalcium/calmodulin-dependent protein kinase II alpha [ Homo sapiens ]
Synonyms : CAMK2A;calcium/calmodulin-dependent protein kinase II alpha; CAMKA; KIAA0968;CaMKIIN alpha; CaMK-II alpha subunit; CaM-kinase II alpha chain; CaM kinaseII alpha subunit; calcium/calmodulin-dependent protein kinase II alpha-Bsubunit; calcium/calmodulin-dependent protein kinase type II alpha chain;calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha; EC2.7.11.17; OTTHUMP00000165787; OTTHUMP00000165788; CaM kinase II subunitalpha; CaMK-II subunit alpha
Gene ID : 815
mRNA Refseq : NM_015981
Protein Refseq : NP_057065
MIM : 114078
UniProt ID : Q9UQM7
Chromosome Location : 5q32
Pathway : Calcium signaling pathway; ErbBsignaling pathway; Glioma; GnRH signaling pathway; Long-term potentiation;Melanogenesis; Neurotrophin signaling pathway; Olfactory transduction; Wntsignaling pathway
Function : ATP binding; calmodulinbinding; calmodulin-dependent protein kinase activity; nucleotide binding;transferase activity

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