"CCL3" Related Products


Recombinant Human Chemokine (C-C motif) Ligand 3

Cat. No.: CCL3-363H
Product Overview: Recombinant humanCCL3 contains 69 amino acid residues was expessed in Inscet cells. Itsmolecular weight is 7700 Dalton.
Description: CCL3 is identical toMIP1-beta (ACT II isotype) except for two amino acid substitutions: argininefor histidine at position 22 and serine for glycine at position 47 of themature protein.
Source: Insect cells
Species: Human
Form: Lyophilized withoutadditives
Molecular Weight: 7.7 kDa
Purity: > 98% asdetermined by SDS-PAGE analysis
Endotoxin Level: < 0.1 ng/µg ofLAG1
Biological Activity: Determined by itsability to chemoattract CCR5 transfected cells using a concentration of0.1-10.0 ng/ml.
Reconstitution: Centrifugevial prior to opening. First add sterile distilled water to the vial to fullysolubilize the protein to a concentration of 0.1-1.0 mg/ml. After completesolubilization of the protein, it can be further diluted to other aqueoussolutions.
Storage: Store lyophilizedprotein at -20°C to -80°C and reconstituted protein in working aliquots at-20°C to -80°C. Avoid repeated freeze-thaw cycles.
OfficialSymbol: CCL3
Gene Name: CCL3 chemokine (C-C motif) ligand 22 [Homo sapiens ]
Synonyms: CCL3; chemokine (C-Cmotif) ligand 3; MIP1A; SCYA3; G0S19-1; LD78ALPHA; MIP-1-alpha; LD78 alphabeta; small inducible cytokine A3 (homologous to mouse Mip-1a); SIS-beta;G0/G1 switch regulatory protein 19-1; G0S19-1 protein; LD78 alpha beta;Macrophage inflammatory protein 1-alpha; PAT 464.1; Small-inducible cytokineA3; Tonsillar lymphocyte LD78 alpha protein; C-C motif chemokine 3;Small-inducible cytokine A3; MIP-1-alpha; Tonsillar lymphocyte LD78 alphaprotein; G0/G1 switch regulatory protein 19-1; G0S19-1 protein; SIS-beta; PAT464.1
Gene ID: 6348
mRNA Refseq: NM_002983
Protein Refseq: NP_002974
MIM: 182283
UniProt ID: P10147
Chromosome Location: 17q11-q21
Pathway: Chemokine signalingpathway; Cytokine-cytokine receptor interaction; Chagas disease (Americantrypanosomiasis); Chemokine receptors bind chemokines; Class A/1(Rhodopsin-like receptors); GPCR ligand binding; IL12-mediated signalingevents; Peptide ligand-binding receptors; Rheumatoid arthritis; Senescenceand Autophagy; Salmonella infection; Signal Transduction; Signaling by GPCR;Toll-like receptor signaling pathway
Function: chemoattractantactivity; chemokine activity; signal transducer activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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