"GRK6" Related Products


Recombinant Human G Protein-Coupled Receptor Kinase 6, GST-tagged

Cat. No. : GRK6-1233H
Product Overview : Recombinant humanfull length GRK6, GST-tagged. No special measures were taken to activate thiskinase.
Description : Thisgene encodes a member of the guanine nucleotide-binding protein (Gprotein)-coupled receptor kinase subfamily of the Ser/Thr protein kinasefamily. The protein phosphorylates the activated forms of G protein-coupledreceptors thus initiating their deactivation. Several transcript variantsencoding different isoforms have been described for this gene. GRK6 appearsto be involved in responses to morphine.
Source : Insect cells
Species : Human
Form : Liquid in 50 mMTris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2 mM DTT +50% glycerol.
Molecular Weight : 94.0 kDa
Purity : ≥ 90% as determinedby SDS-PAGE analysis
Storage : Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles.
OfficialSymbol : GRK6
PDBrendering based on 2acx. :

Gene Name : GRK6 G protein-coupled receptorkinase 6 [ Homo sapiens ]
Synonyms : GRK6; G protein-coupledreceptor kinase 6; GPRK6; FLJ32135; G protein-coupled receptor kinase 6;OTTHUMP00000223834; OTTHUMP00000223835; OTTHUMP00000223836;OTTHUMP00000231482; OTTHUMP00000231483; g protein-coupled receptor kinaseGRK6
Gene ID : 2870
mRNA Refseq : NM_001004105
Protein Refseq : NP_001004105
MIM : 600869
UniProt ID : P43250
Chromosome Location : 5q35
Pathway : CXCR4-mediated signalingevents; Chemokine signaling pathway; Chemokine signaling pathway; Endocytosis;Myometrial Relaxation and Contraction Pathway
Function : ATP binding; G-protein coupledreceptor kinase activity; nucleotide binding; signal transducer activity

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