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Native Rat Plasminogen

Cat. No.: Plg-1897R
Product Overview: Native rat Plg wasexpressed in rat plasma.
Description: Plg is acirculating zymogen that is converted to the active enzyme Plasminby cleavage of the peptide bond between Arg-560 and Val-561, which is mediatedby Urokinase (uPA/PLAU) and Tissue Plasminogen Activator (tPA/PLAT). The mainfunction of Plasmin is to dissolve Fibrin blood clots. Plasmin, like Trypsin,belongstothe family of serine proteases Fibrin is a cofactor for Plasminogenactivation by tPA.
Form: Frozen Liquid in 0.1M HEPES + 0.1 M NaCl pH 7.4.
Source: Rat plasma
Molecular Weight: 85 kDa
Concentration: 10.0 mg/mL
Storage: Store at -70°C.
Pathways: Blood ClottingCascade; Complement and Coagulation Cascades; Complement and coagulationcascades; Diabetes pathways; Dissolution of Fibrin Clot; Hemostasis;Influenza A; LDL-mediated lipid transport; Lipid digestion; Lipoproteinmetabolism; Metabolism of lipids and lipoproteins; Neuroactiveligand-receptor interaction; Platelet activation; Platelet degranulation;Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-likeGrowth Factor Binding Proteins (IGFBPs)
Gene Name: Plg plasminogen [ Rattusnorvegicus ]
Official Symbol: Plg
Synonyms: Plg; plasminogen; Ab1-346
Gene ID: 85253
mRNA Refseq: NM_053491
Protein Refseq: NP_445943
Chromosome Location: 1q11
Function: apolipoproteinbinding; cell surface binding; endopeptidase activity; peptidase activity;serine-type endopeptidase activity

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