||Native rat Plg wasexpressed in rat plasma.
||Plg is acirculating zymogen that is converted to the active enzyme Plasminby cleavage of the peptide bond between Arg-560 and Val-561, which is mediatedby Urokinase (uPA/PLAU) and Tissue Plasminogen Activator (tPA/PLAT). The mainfunction of Plasmin is to dissolve Fibrin blood clots. Plasmin, like Trypsin,belongstothe family of serine proteases Fibrin is a cofactor for Plasminogenactivation by tPA.
||Frozen Liquid in 0.1M HEPES + 0.1 M NaCl pH 7.4.
||Store at -70°C.
||Blood ClottingCascade; Complement and Coagulation Cascades; Complement and coagulationcascades; Diabetes pathways; Dissolution of Fibrin Clot; Hemostasis;Influenza A; LDL-mediated lipid transport; Lipid digestion; Lipoproteinmetabolism; Metabolism of lipids and lipoproteins; Neuroactiveligand-receptor interaction; Platelet activation; Platelet degranulation;Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-likeGrowth Factor Binding Proteins (IGFBPs)