Native Rat Plasminogen


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Native Rat Plasminogen

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Cat. No. : Plg-1897R
Product Overview : Native rat Plg wasexpressed in rat plasma.
Description : Plg is acirculating zymogen that is converted to the active enzyme Plasminby cleavage of the peptide bond between Arg-560 and Val-561, which is mediatedby Urokinase (uPA/PLAU) and Tissue Plasminogen Activator (tPA/PLAT). The mainfunction of Plasmin is to dissolve Fibrin blood clots. Plasmin, like Trypsin,belongstothe family of serine proteases Fibrin is a cofactor for Plasminogenactivation by tPA.
Form : Frozen Liquid in 0.1M HEPES + 0.1 M NaCl pH 7.4.
Source : Rat plasma
Molecular Weight : 85 kDa
Concentration : 10.0 mg/mL
Storage : Store at -70°C.
Pathways : Blood ClottingCascade; Complement and Coagulation Cascades; Complement and coagulationcascades; Diabetes pathways; Dissolution of Fibrin Clot; Hemostasis;Influenza A; LDL-mediated lipid transport; Lipid digestion; Lipoproteinmetabolism; Metabolism of lipids and lipoproteins; Neuroactiveligand-receptor interaction; Platelet activation; Platelet degranulation;Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-likeGrowth Factor Binding Proteins (IGFBPs)
PDB rendering based on 1b2i. :

Gene Name : Plg plasminogen [ Rattusnorvegicus ]
Official Symbol : Plg
Synonyms : Plg; plasminogen; Ab1-346
Gene ID : 85253
mRNA Refseq : NM_053491
Protein Refseq : NP_445943
Chromosome Location : 1q11
Function : apolipoproteinbinding; cell surface binding; endopeptidase activity; peptidase activity;serine-type endopeptidase activity

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