Recombinant Human Leucine Rich Repeat Containing 4, His-tagged

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Recombinant Human Leucine Rich Repeat Containing 4, His-tagged

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Cat. No. : LRRC4-5680H
Product Overview : Recombinant Human LRRC4protein was expressed in CHO with a C-terminal 6-His tag. Ala39-Lys527.
Description : LRRC4, also called NGL2or NAG14 is a 55 kDa (predicted) type I transmembrane protein that is amember of the NGL family of synaptic LRR adhesion molecules. Human LRRC4 cDNAencodes 653 amino acids (aa) that include a 38 aa signal sequence, a 489 aaextracellular domain (ECD), a 21 aa transmembrane domain, and a 105 aacytoplasmic domain. The ECD contains nine LRRs (aa 74-288), a C2 type Ig likedomain (aa 354-440), and a Thr-rich segment (aa 455-526).
Source : Chinese HamsterOvary cell line, CHO-derived.
Form : Lyophilized from a0.2 μm filtered solution in PBS.
N-terminalSequence : Ala39
Molecular Weight : 55.6 kDa
Activity : Measuredby its binding ability in a functional ELISA. When rmNetrinG2a/Fc is coatedat 5 μg/mL, rhLRRC4 binds with an apparent KD < 10 nM.
Endotoxin Level : <1.0 EUper 1 μg of the protein by the LAL method.
SDS-PAGE : 90-110kDa, reducing conditions.
Purity : >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : 400μg/mL in PBS
Storage : Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months fromdate of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterileconditions after reconstitution. 3 months, -20 to -70°C under sterileconditions after reconstitution.
PDBrendering based on 2dl9. :

Gene Name : LRRC4 leucine rich repeatcontaining 4 [ Homo sapiens ]
Official Symbol : LRRC4
Synonyms : LRRC4; leucine richrepeat containing 4; NAG14; NGL-2; MGC133342; MGC133343; leucine-richrepeat-containing protein 4; netrin-G2 ligand; leucine-rich repeat-containing4; brain tumor-associated protein BAG; brain tumor associated protein LRRC4;nasopharyngeal carcinoma-associated gene 14 protein; UNQ554/PRO1111; BAG;OTTHUMP00000212281; OTTHUMP00000212284
Gene ID : 64101
mRNA Refseq : NM_022143
Protein Refseq : NP_071426
MIM : 610486
UniProt ID : Q9HBW1
Chromosome Location : 7q31
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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