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Active Recombinant Mouse Bone Morphogenetic Protein 10

Cat.No. : Bmp10-575M
Product Overview : Recombinant Mouse Bmp10protein was expressed in Chinese Hamster Ovary cell line. Asn314-Arg421.
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  • Gene Information
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Cat. No. : Bmp10-575M
Description : Bmp10, along with BMP9,GDF5, 6, and 7, belongs to a subgroup of TGFβ superfamily proteins thatsignal through heterodimeric complexes composed of type I and type II BMPreceptors. Proteolytic removal of the propeptide from the 60 kDa proproteinyields a 12 kDa mature Bmp10 which forms disulfidelinked nonglycosylatedhomodimers.
Source : Chinese HamsterOvary cell line, CHO-derived.
Form : Lyophilized from a0.2 μm filtered solution in PBS.
N-terminalSequence : Asn314
Molecular Weight : 12.1 kDa (monomer)
Activity : Measured by itsability to induce alkaline phosphatase production by MC3T3-E1 mouseosteoblastic cells. The ED50 for this effect is typically 15-75 ng/mL.
Endotoxin Level : < 1.0 EU per 1 μgof the protein by the LAL method.
SDS-PAGE : 10 kDa,reducing conditions.
Purity : > 95%, by SDSPAGEunder reducing conditions and visualized by silver stain.
Reconstitution : 250 μg/mL in 4 mMHCl containing at least 0.1% human or bovine serum albumin.
Storage : Use a manualdefrost freezer and avoid repeated freeze-thaw cycles. 12 months from date ofreceipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterile conditionsafter reconstitution. 3 months, -20 to -70°C under sterile conditions after reconstitution.
Gene Name : Bmp10 bone morphogeneticprotein 10 [ Mus musculus ]
Official Symbol : Bmp10
Synonyms : Bmp10; bonemorphogenetic protein 10; BMP-10
Gene ID : 12154
mRNA Refseq : NM_009756
Protein Refseq : NP_033886
Chromosome Location : 6; 6 D2
Function : cytokine activity;growth factor activity; receptor serine/threonine kinase binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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