"BMP8A" Related Products


Recombinant Human Bone Morphogenetic Protein 8a

Cat. No. : BMP8A-587H
Product Overview : Recombinant Human BMP8Aprotein was expressed in Chinese Hamster Ovary cell line. Ala264-His402.
Description : BMP8A, also known asosteogenic protein 2 (OP-2), was first isolated from a hippocampal library ina screen to identify relatives of BMP-7/OP-1. BMPs are a family ofstructurally and functionally related proteins and represent a subfamily ofthe transforming growth factor β (TGF-β) superfamily. BMPs are involved in awide range of processes including embryogenesis, tissue morphogenesis, cell differentiationand migration, and tumorigenesis. Cellular responses to BMPs are mediated by heterooligomericcomplexes of type I and type II serine/threonine kinase receptors.
Source : Chinese HamsterOvary cell line, CHO-derived.
Form : Lyophilized from a0.2 μm filtered solution in HCl.
N-terminalSequence : Ala264
Molecular Weight : 15.7 kDa (monomer)
Activity : Measured by itsability to inhibit the cell growth of DU145 human prostate carcinoma cells. TheED50 for this effect is typically 0.2-1 μg/mL.
Endotoxin Level : < 1.0EU per 1 μg of the protein by the LAL method.
SDS-PAGE : 19 kDa,reducing conditions.
Purity : > 95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : 250 μg/mL in 4 mMHCl.
Storage : Use a manualdefrost freezer and avoid repeated freeze-thaw cycles. 12 months from date ofreceipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterile conditionsafter reconstitution. 3 months, -20 to -70°C under sterile conditions after reconstitution.
Gene Name : BMP8A bone morphogeneticprotein 8a [ Homo sapiens ]
Official Symbol : BMP8A
Synonyms : BMP8A; bonemorphogenetic protein 8a; bone morphogenetic protein 8A; BMP-8A
Gene ID : 353500
mRNA Refseq : NM_181809
Protein Refseq : NP_861525
UniProt ID : Q7Z5Y6
Chromosome Location : 1p35-p32
Pathway : Hedgehog signalingpathway; TGF-beta signaling pathway
Function : cytokine activity;growth factor activity

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