"FCRLB" Related Products


Recombinant Human Fc Receptor-Like B, His-tagged

Cat. No.: FCRLB-512H
Product Overview: RecombinantHuman FCRLB protein was expressed in Murine myeloma cellline. Ala18-Ser426,with a C-terminal 6-His tag.
Description: FCRLB isa 60 kDa protein with sequence homology to classical Fc receptors. There areat least six type 1 transmembrane FCRL proteins and two that lack transmembranesegments. Each family member contains between three and nine immunoglobulin-likedomains. FCRL proteins are differentially expressed within the B cell lineageand can either promote or inhibit B cell proliferation and activation. Accordingto R&D Systems testing, FCRLB binds to purified human IgG with highaffinity. Human FCRLB shares 82% and 85% amino acid sequence identity withmouse and rat FCRLB, respectively. It contains a putative signal peptide,three immunoglobulin-like domains, and a mucinlike stalk that is rich in Pro,Ser, and Thr residues.
Source: Murine myeloma cellline, NS0-derived.
Form: Lyophilized from a0.2 um filtered solution in PBS and EDTA.
N-terminalSequence: Ala18
MolecularWeight: 46 kDa
Activity: Measuredby its ability to bind human IgG with an estimated KD < 120 nM.
Endotoxin Level: <1.0EU per 1μg of the protein by the LAL method.
SDS-PAGE: 65-70kDa, reducing conditions.
Purity: >90%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution: Reconstitute at 100μg/mLin PBS.
Storage: Use amanual defrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution.
Gene Name: FCRLB Fc receptor-like B [ Homosapiens ]
Official Symbol: FCRLB
Synonyms: FCRLB; Fc receptor-like B; Fc receptorlike and mucin like 2; FCRLM2; FCRL2; FCRLY; FLJ31052; FREB2; RP11-474I16.6;Fc receptor homolog expressed in B cells protein 2; Fc receptor like B; Fcreceptor like mucin like 2; Fc receptor like protein 2; Fc receptor relatedY; Fcry; mFCRL2; RGD1563018; fc receptor-like and mucin-like protein 2; FcRY;FREB-2
Gene ID: 127943
mRNA Refseq: NM_001002901
Protein Refseq: NP_001002901
MIM: 609251
UniProt ID: Q6BAA4
Chromosome Location: 1q23.3

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.