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Active Recombinant Human Fc Receptor-Like B, His-tagged

Cat.No. : FCRLB-512H
Product Overview : RecombinantHuman FCRLB protein was expressed in Murine myeloma cellline. Ala18-Ser426,with a C-terminal 6-His tag.
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Cat. No. : FCRLB-512H
Description : FCRLB isa 60 kDa protein with sequence homology to classical Fc receptors. There areat least six type 1 transmembrane FCRL proteins and two that lack transmembranesegments. Each family member contains between three and nine immunoglobulin-likedomains. FCRL proteins are differentially expressed within the B cell lineageand can either promote or inhibit B cell proliferation and activation. Accordingto R&D Systems testing, FCRLB binds to purified human IgG with highaffinity. Human FCRLB shares 82% and 85% amino acid sequence identity withmouse and rat FCRLB, respectively. It contains a putative signal peptide,three immunoglobulin-like domains, and a mucinlike stalk that is rich in Pro,Ser, and Thr residues.
Source : Mammalian cells
Form : Lyophilized from a0.2 um filtered solution in PBS and EDTA.
N-terminalSequence : Ala18
MolecularWeight : 46 kDa
Activity : Measuredby its ability to bind human IgG with an estimated KD < 120 nM.
Endotoxin Level : <1.0EU per 1μg of the protein by the LAL method.
SDS-PAGE : 65-70kDa, reducing conditions.
Purity : >90%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : Reconstitute at 100μg/mLin PBS.
Storage : Use amanual defrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution.
Gene Name : FCRLB Fc receptor-like B [ Homosapiens ]
Official Symbol : FCRLB
Synonyms : FCRLB; Fc receptor-like B; Fc receptorlike and mucin like 2; FCRLM2; FCRL2; FCRLY; FLJ31052; FREB2; RP11-474I16.6;Fc receptor homolog expressed in B cells protein 2; Fc receptor like B; Fcreceptor like mucin like 2; Fc receptor like protein 2; Fc receptor relatedY; Fcry; mFCRL2; RGD1563018; fc receptor-like and mucin-like protein 2; FcRY;FREB-2
Gene ID : 127943
mRNA Refseq : NM_001002901
Protein Refseq : NP_001002901
MIM : 609251
UniProt ID : Q6BAA4
Chromosome Location : 1q23.3

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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