"FCRLB" Related Products


Recombinant Human Fc Receptor-Like B, His-tagged

Cat. No. : FCRLB-512H
Product Overview : RecombinantHuman FCRLB protein was expressed in Murine myeloma cellline. Ala18-Ser426,with a C-terminal 6-His tag.
Description : FCRLB isa 60 kDa protein with sequence homology to classical Fc receptors. There areat least six type 1 transmembrane FCRL proteins and two that lack transmembranesegments. Each family member contains between three and nine immunoglobulin-likedomains. FCRL proteins are differentially expressed within the B cell lineageand can either promote or inhibit B cell proliferation and activation. Accordingto R&D Systems testing, FCRLB binds to purified human IgG with highaffinity. Human FCRLB shares 82% and 85% amino acid sequence identity withmouse and rat FCRLB, respectively. It contains a putative signal peptide,three immunoglobulin-like domains, and a mucinlike stalk that is rich in Pro,Ser, and Thr residues.
Source : Murine myeloma cellline, NS0-derived.
Form : Lyophilized from a0.2 um filtered solution in PBS and EDTA.
N-terminalSequence : Ala18
MolecularWeight : 46 kDa
Activity : Measuredby its ability to bind human IgG with an estimated KD < 120 nM.
Endotoxin Level : <1.0EU per 1μg of the protein by the LAL method.
SDS-PAGE : 65-70kDa, reducing conditions.
Purity : >90%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : Reconstitute at 100μg/mLin PBS.
Storage : Use amanual defrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution.
Gene Name : FCRLB Fc receptor-like B [ Homosapiens ]
Official Symbol : FCRLB
Synonyms : FCRLB; Fc receptor-like B; Fc receptorlike and mucin like 2; FCRLM2; FCRL2; FCRLY; FLJ31052; FREB2; RP11-474I16.6;Fc receptor homolog expressed in B cells protein 2; Fc receptor like B; Fcreceptor like mucin like 2; Fc receptor like protein 2; Fc receptor relatedY; Fcry; mFCRL2; RGD1563018; fc receptor-like and mucin-like protein 2; FcRY;FREB-2
Gene ID : 127943
mRNA Refseq : NM_001002901
Protein Refseq : NP_001002901
MIM : 609251
UniProt ID : Q6BAA4
Chromosome Location : 1q23.3

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