Active Recombinant Mouse Glypican 2 (cerebroglycan), His-tagged
Cat.No. : | Gpc2-5625M |
Product Overview : | RecombinantMouse Gpc2 protein was expressed in Murine myeloma cell line. Lys27-Arg358& Ala359-Leu554, with a C-terminal 6-His tag. |
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Cat. No. : | Gpc2-5625M |
Description : | Theglypicans (GPC) constitute a family of heparan sulfate proteoglycans that areattached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor.Six members of this family have been identified in mammals (GPC1-GPC6). Allglypican core proteins contain an N-terminal signal peptide, a large globularcysteine-rich domain (CRD) with 14 invariant cysteine residues, a stalk-likeregion containing the heparan sulfate attachment sites, and a C-terminal GPIattachment site. Based on the degree of their amino acid sequence similarity,two subfamilies of glypicans have been defined. |
Source : | Mammalian cells |
Form : | Lyophilized from a0.2 um filtered solution in Tris-Citrate and NaCl. |
N-terminalSequence : | Lys27 & Ala359 |
MolecularWeight : | 58.9 kDa |
Activity : | Measuredby its binding ability in a functional ELISA. Immobilized rm Gpc2 at 4μg/mL(100μL/well) can bind rhMidkine with a linear range of 4-200 ng/mL. |
Endotoxin Level : | <1.0EU per 1μg of the protein by the LAL method. |
SDS-PAGE : | 60 kDa, non-reducingconditions. |
Purity : | >95%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Reconstitution : | Reconstituteat 100μg/mL in PBS. |
Storage : | Use a manual defrost freezer and avoid repeated freezethawcycles. 12months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °Cunder sterile conditions after reconstitution. 3 months, -20 to -70 °C understerile conditions after reconstitution. |
Gene Name : | Gpc2 glypican 2 (cerebroglycan)[ Mus musculus ] |
Official Symbol : | Gpc2 |
Synonyms : | Gpc2; glypican 2(cerebroglycan); 2410016G05Rik; glypican-2 |
Gene ID : | 71951 |
mRNA Refseq : | NM_172412 |
Protein Refseq : | NP_766000 |
UniProt ID : | Q3TU56 |
Chromosome Location : | 5 |
Function : | heparan sulfateproteoglycan binding |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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